Seronegative spondarthritis

"Seronegative" refers to the fact that these diseases are negative for Rheumatoid Factor and CCP in the serum.

Seronegative spondyloarthritis is a group of diseases, including:

* psoriatic arthritis
* Reiter's disease
* arthritis in association with inflammatory bowel disease
* ankylosing spondylitis
* Behcet's syndrome
* Whipple's disease

These diseases has following conditions in common:
* They are in relation to HLA-B27
* sacroiliitis and spondylitis are present in them.
* familial aggregation occurs
* Overlap is likely in them
* rheumatoid factor is not present

References

*http://www.gpnotebook.co.uk/cache/-254803955.htm