Pneumotaxic center

Pneumotaxic center

The pneumotaxic center, also known as the pontine respiratory group (PRG), is a network of neurons in the rostral dorsal lateral pons. It consists of the Kölliker-Fuse nucleus and the medial parabrachial nucleus. [cite journal|author=Song G, Yu Y, Poon C |title=Cytoarchitecture of pneumotaxic integration of respiratory and nonrespiratory information in the rat|journal=J Neurosci|volume=26|issue=1 |pages=300–10|year=2006|pmid=16399700 |doi=10.1523/JNEUROSCI.3029-05.2006]

Respiratory effects

The PRG antagonises the apneustic center, cyclically inhibiting inspiration. The PRG limits the burst of action potentials in the phrenic nerve, effectively decreasing the tidal volume and regulating the respiratory rate. Absence of the PRG results in an increase in depth of respiration and a decrease in respiratory rate.

External links

* [http://www.people.vcu.edu/~mikuleck/courses/resp2/sld021.htm Description at vcu.edu]

References

#cite book|last=Levitzky|first=Michael G.|title=Pulmonary Physiology, 6th edition|publisher=McGraw-Hill Professional|date=2002|location=|pages=193-4|isbn=007138765X
#cite book|last=Costanzo|first=Linda S.|title=Physiology, 3rd edition|publisher=Elsevier|date=2006|location=Philadelphia, PA|pages=224|isbn=978-1-4160-2320-3
#cite journal|author=Roger Shannon, David M. Baekey, Kendall F. Morris, Sarah C. Nuding, Lauren S. Segers and Bruce G. Lindsey|title=Pontine respiratory group neuron discharge is altered during fictive cough in the decerebrate cat|journal=Respiratory Physiology & Neurobiology|volume=142|issue=1|pages=43–54|year=2004|doi=10.1016/j.resp.2004.05.002


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  • pneumotaxic center — pneu·mo·tax·ic center .n(y)ü mə tak sik n a neural center in the upper part of the pons that provides inhibitory impulses on inspiration and thereby prevents overdistension of the lungs and helps to maintain alternately recurrent inspiration and… …   Medical dictionary

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  • Apneustic center — The apneustic center of the lower pons appears to promote inspiration by stimulation of the I neurons in the medulla oblongata providing a constant stimulus.The apneustic centre of pons sends signals to the dorsal respiratory centre in the… …   Wikipedia

  • Control of respiration — Control of ventilation refers to the physiological mechanisms involved in the control of physiologic ventilation. Gas exchange primarily controls the rate of respiration. The most important function of breathing is gas exchange (of oxygen and… …   Wikipedia

  • Medial parabrachial nucleus — Brain: Medial parabrachial nucleus Latin nucleus parabrachialis medialis NeuroNames hier 757 NeuroLex ID birnlex 4038 The Medial parabrachial nuc …   Wikipedia

  • Respiratory system — See also: Respiratory tract Respiratory A complete, schematic view of the human respiratory system with their parts and functions. Latin …   Wikipedia

  • Tegmental pontine reticular nucleus — Brain: Tegmental pontine reticular nucleus Latin nucleus reticularis tegmenti pontis NeuroNames hier 563 The tegmental pontine reticular nucleus (or pontine reticular nucleus of the tegmentum) is an area within the floor of the midbrain. This… …   Wikipedia

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