Phlegmasia cerulea dolens
- Phlegmasia cerulea dolens
Infobox_Disease
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DiseasesDB = 32484
ICD10 =
ICD9 =
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OMIM =
MedlinePlus = 000200
eMedicineSubj = med
eMedicineTopic = 2767
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Phlegmasia cerulea dolens is an uncommon severe form of deep venous thrombosis which results from extensive thrombotic occlusion of the major and the collateral veins of an extremity. It is characterized by sudden severe pain, swelling, cyanosis and edema of the affected limb. There is a high risk of massive pulmonary embolism, even under anticoagulation. Foot gangrene may also occur.
This phenomenon was discovered by Jonathan Towne, a vascular surgeon in Milwaukee, who was also the first to report the "white clot syndrome" (Now called HIT= Heparin induced thrombocytopenia). Two of their HIT patients developed Phlegmasia cerulea dolens that went on to become gangrenous [Heparin-Induced Thrombocytopenia By Theodore E. Warkentin, Andreas Greinacher, Published 2004, ISBN 0824756258] .
References
*Cite journal|title=Images in Clinical Medicine: Phlegmasia Cerulea Dolens|last=Barham|first=Kalleen|coauthors=Tina Shah|date=2007 Jan 18|journal=The New England Journal of Medicine|volume=356|issue=3|pages=e3|pmid=17229945
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