Para-Aminohippurate

Para-Aminohippurate

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ImageFile=p-Aminohippurate sodium.svg
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IUPACName=sodium 2- [(4-aminobenzoyl)amino] acetate
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PubChem=7178
SMILES=C1=CC(=CC=C1C(=O)NCC(=O) [O-] )N. [Na+]
Section2= Chembox Properties
Formula=C9H9N2NaO3
MolarMass=216.169 g/mol
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"para"-Aminohippurate (PAH) is a substance used in the measurement of renal blood flow. It is useful in this measurement because it is primarily secreted by the renal tubules; only 20-30% is filtered by the glomerulus. cite journal|title=Effect of 20,60 and 120 minutes of renal ischemia on glomerular and tubular function|journal=Am J Physiol|date=1948-02-29|first=R. A.|last=Phillips|coauthors=P. B. Hamilton|volume=152|issue=3|pages=523–30|issn=0002-9513|id= |url=http://ajplegacy.physiology.org/cgi/content/citation/152/3/523|format=PDF|accessdate=2008-03-20 ]

The renal extraction ratio of PAH is a normal individual is approximately 0.92.cite journal | author = Reubi, François C. | title = Glomerular filtration rate, renal blood flow and blood viscosity during and after diabetic coma | journal = Circ. Res. | volume = 1 | issue = 5 | pages = 410–3 | year = 1953-04-29 | pmid = 13082682 | doi = | issn = 00097330 | url=http://circres.ahajournals.org/cgi/content/abstract/1/5/410 | accessdate = 2008-03-19]

References

Further reading

*PAH clearance

External links

* [http://ajplegacy.physiology.org/cgi/reprint/152/3/523.pdf "Effect of 20,60 and 120 minutes of renal ischemia on glomerular and tubular function"] (subscription may be necessary)
* [http://circres.ahajournals.org/cgi/reprint/1/5/410.pdf "Glomerular filtration rate, renal blood flow and blood viscosity during and after diabetic coma"] (subscription may be necessary)


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Look at other dictionaries:

  • para-aminohippurate — para ami·no·hip·pu·rate hip yə .rāt n a salt of para aminohippuric acid …   Medical dictionary

  • Aminohippuric acid — Aminohippurate Systematic (IUPAC) name 2 [(4 Aminobenzoyl)amino]acetic acid Clinical data Pregnancy cat.  ? …   Wikipedia

  • Cpah — para aminohippurate clearance …   Medical dictionary

  • Cpah — • para aminohippurate clearance …   Dictionary of medical acronyms & abbreviations

  • PAH — • para aminohippurate; • phenylalanine hydroxylase; • polycyclic aromatic hydrocarbon; • predicted adult height [by Bayley Pinneau]; • pulmonary alveolar hypoventilation; • pulmonary artery hypertension; • pulmonary artery hypotension …   Dictionary of medical acronyms & abbreviations

  • Acide aminohippurique — Général Nom IUPAC acide 2 [(4 aminobenzoyl)amino]acétique Synonymes …   Wikipédia en Français

  • PAH — Abbreviation for p aminohippuric acid. * * * para aminohippurate; phenylalanine hydroxylase; polycyclic aromatic hydrocarbon; predicted adult height [by Bayley Pinneau]; pulmonary alveolar hypoventilation; pulmonary artery hypertension; pulmonary …   Medical dictionary

  • PAH clearance — Parameter Value renal blood flow RBF=1000 ml/min hematocrit HCT=40% renal plasma flow RPF=600 ml/min filtration fraction FF=20% glomerular filtration rate GFR=120 ml/min …   Wikipedia

  • Organic anion transporter 1 — Figure 1 Schematic representation of transmembrane proteins: 1. a membrane protein with one transmembrane domain 2. a membrane protein with three transmembrane domains 3. OAT1 is believed to have twelve transmembrane domains. [1] The membrane is… …   Wikipedia

  • PAH — or Pah may refer to: In chemistry and biology: Polycyclic aromatic hydrocarbon, one of a class of chemical compounds, organic pollutants Phenylalanine hydroxylase, an enzyme involved in breaking down phenylalanine Para aminohippurate, a substance …   Wikipedia

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