Intermediate-density lipoprotein

Intermediate-density lipoprotein

Intermediate-density lipoproteins belong to the lipoprotein particle family and are formed from the degradation of very low-density lipoproteins. IDL is one of the five major groups of lipoproteins (chylomicrons, VLDL, IDL, LDL, HDL) which enable fats and cholesterol to move within the water based solution of the blood stream. Each native IDL particle consists of protein that encircles various fatty acids; enabling, as a water soluble particle, these fatty acids to travel in the aqueous blood environment as part of the fat transport system within the body. Their size is generally 25 to 35 nm in diameter and they primarily contain a range of triacylglycerols and cholesterol esters. They are cleared from the plasma into the liver by receptor-mediated endocytosis, or further degraded to form LDL particles.

Generally, IDL, somewhat similar to low-density lipoprotein (LDL), transports a variety of triglyceride fats and cholesterol and, like LDL, can also promote the growth of atheroma.


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  • Intermediate Density Lipoprotein — Lipoproteine sind nicht kovalente Aggregate aus Lipid und Protein und bilden mizellenähnliche Partikel mit einem unpolaren Kern aus Cholesterinestern und Triglyceriden und einer zur wässrigen Phase gerichteten Hülle mit polaren, hydrophilen… …   Deutsch Wikipedia

  • Intermediate Density Lipoprotein — Lipoprotéine de densité intermédiaire Pour les articles homonymes, voir IDL. Les lipoprotéine de densité intermédiaire ou IDL pour Intermediate Density Lipoprotein en anglais sont des lipoprotéines responsables du transport de molécules de… …   Wikipédia en Français

  • intermediate-density lipoprotein — (IDL) a class of lipoproteins formed in the degradation of very low density lipoproteins; approximately half are cleared rapidly from the plasma into the liver by receptor mediated endocytosis; the other half are further degraded to form low… …   Medical dictionary

  • Low-density lipoprotein — (LDL) is a type of lipoprotein that transports cholesterol and triglycerides from the liver to peripheral tissues. LDL is one of the five major groups of lipoproteins; these groups include chylomicrons, very low density lipoprotein (VLDL),… …   Wikipedia

  • Very low density lipoprotein — (VLDL) ist ein Bestandteil des Blutplasmas, und dient dem Transport von Triglyceriden, Cholesterin und Phospholipiden von der Leber zu den Geweben. Auf seinem Weg wandelt es sich durch Abgabe der Triglyceride von VLDL allmählich in LDL um. VLDLs… …   Deutsch Wikipedia

  • Very low-density lipoprotein — (VLDL) is a type of lipoprotein made by the liver. VLDL is one of the five major groups of lipoproteins (chylomicrons, VLDL, IDL, LDL, HDL) which enable fats and cholesterol to move within the water based solution of the blood stream. It is… …   Wikipedia

  • Very Low Density Lipoprotein — (VLDL) ist ein Bestandteil des Blutplasmas, und dient dem Transport von Triglyceriden, Cholesterin und Phospholipiden von der Leber zu den Geweben. Auf seinem Weg wandelt es sich durch die allmähliche Abgabe der Triglyceride von VLDL in LDL um.… …   Deutsch Wikipedia

  • High Density Lipoprotein — bzw. Lipoprotein hoher Dichte ist eine von mehreren Lipoprotein Klassen im menschlichen Körper, die aus historischen Gründen nach ihrem Verhalten in der Ultrazentrifuge – und damit nach ihrer Dichte („density“) – klassifiziert werden. Die… …   Deutsch Wikipedia

  • low-density lipoprotein — low den·si·ty lipoprotein lō den(t) sət ē n LDL * * * (LDL) see lipoprotein * * * (LDL) a class of lipoproteins responsible for transport of cholesterol to extrahepatic tissues. It is formed in the circulation when very low density lipoproteins… …   Medical dictionary

  • very-low-density lipoprotein — ver ē n VLDL * * * (VLDL) a class of lipoproteins that transport triglycerides from the intestine and liver to adipose and muscle tissues. Synthesized by the liver, they contain primarily triglycerides in their lipid cores, with some cholesteryl… …   Medical dictionary

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