- Fox-Fordyce disease
Infobox_Disease
Name = PAGENAME
Caption =
DiseasesDB = 30029
ICD10 = ICD10|L|75|2|l|60
ICD9 = ICD9|705.82
ICDO =
OMIM =
MedlinePlus =
eMedicineSubj = derm
eMedicineTopic = 160
MeshID = D005588Fox-Fordyce disease, or apocrine miliaria, is a
chronic blockage of thesweat gland ducts with a secondary, nonbacteria l inflammatory response to thesecretion s and cellular debris in thecyst s.Hidradenitis is very similar but tends to have a secondary bacterial infection so that pus-draining sinuses are formed. It is a very devastatingskin disease that does not have universally curative treatments.Eponym
It is named for George Henry Fox and
John Fordyce . [WhoNamedIt|synd|1512] [G. H. Fox, J. A. Fordyce. Two cases of a rare papular disease affecting the axillary region. Journal of Cutaneous and Genitourinary Diseases, Chicago, 1902, 20: 1-5.]Treatment
The mainstay treatment is surgical removal of the skin tissue containing affected sweat glands.
Irradiation therapy may also be used andantibiotic s are used to reduce the inflammatory response.No treatment is required for Fordyce granules, except for cosmetic removal of labial lesions. Inflamed glands can be treated topically with
clindamycin . When surgically excised, recurrence does not occur. Neoplastic transformation is very rare but has been reported.References
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