Fox-Fordyce disease

Fox-Fordyce disease

Infobox_Disease
Name = PAGENAME


Caption =
DiseasesDB = 30029
ICD10 = ICD10|L|75|2|l|60
ICD9 = ICD9|705.82
ICDO =
OMIM =
MedlinePlus =
eMedicineSubj = derm
eMedicineTopic = 160
MeshID = D005588

Fox-Fordyce disease, or apocrine miliaria, is a chronic blockage of the sweat gland ducts with a secondary, nonbacterial inflammatory response to the secretions and cellular debris in the cysts. Hidradenitis is very similar but tends to have a secondary bacterial infection so that pus-draining sinuses are formed. It is a very devastating skin disease that does not have universally curative treatments.

Eponym

It is named for George Henry Fox and John Fordyce. [WhoNamedIt|synd|1512] [G. H. Fox, J. A. Fordyce. Two cases of a rare papular disease affecting the axillary region. Journal of Cutaneous and Genitourinary Diseases, Chicago, 1902, 20: 1-5.]

Treatment

The mainstay treatment is surgical removal of the skin tissue containing affected sweat glands. Irradiation therapy may also be used and antibiotics are used to reduce the inflammatory response.

No treatment is required for Fordyce granules, except for cosmetic removal of labial lesions. Inflamed glands can be treated topically with clindamycin. When surgically excised, recurrence does not occur. Neoplastic transformation is very rare but has been reported.

References


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Look at other dictionaries:

  • Fox-Fordyce disease — Fox For·dyce disease (foksґ forґdīs) [G.H. Fox, American dermatologist, 1846–1937; John Addison Fordyce, American dermatologist, 1858–1925] see under disease …   Medical dictionary

  • Fox-Fordyce disease — a chronic, usually pruritic disease seen chiefly in women, characterized by small follicular papular eruptions in apocrine gland–bearing areas such as the axillae and groin. It is caused by obstruction and rupture of the intraepidermal portion… …   Medical dictionary

  • Fordyce disease granule (spot) — For·dyce disease, granule (spot) (forґdīs) [John Addison Fordyce, American dermatologist, 1858–1925] see Fox Fordyce disease, under disease, and see under granule …   Medical dictionary

  • Fordyce disease — 1. see under granule. 2. Fox Fordyce d …   Medical dictionary

  • Fordyce — is a surname, and may refer to* Brook Fordyce * Bruce Fordyce * Daryl Fordyce * George Fordyce * James Fordyce, compiler and primary author of Fordyce s Sermons * Samuel W. Fordyceee also* Fordyce, Arkansas, USA * Fordyce, Nebraska, USA * Fordyce …   Wikipedia

  • Disease — Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the… …   Medical dictionary

  • Fordyce — John A., U.S. dermatologist, 1858–1925. See F. angiokeratoma, F. disease, F. granules, under granule, F. spots, under spot, Fox F. disease …   Medical dictionary

  • Fox — George H., U.S. dermatologist, 1846–1937. See F. Fordyce disease. Lewis, U.S. periodontist, *1903. See Goldman F. knives, under knife. * * * ferrous xylenol orange …   Medical dictionary

  • John Addison Fordyce — (born 16 February 1858 in Guernsey County, Ohio, died on 4 June 1925) was an American dermatologist, whose name is associated with Fordyce s spot, Brooke Fordyce trichoepithelioma, Fordyce s disease, Fordyce s lesion, and Fox Fordyce… …   Wikipedia

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