- Eva Nogales
Dr. Eva Nogales (b. Madrid, Spain) is a
biophysicist at theLawrence Berkeley National Laboratory . She is a Professor of Biochemistry and Molecular Biology at the [http://www.berkeley.edu/ University of California, Berkeley] and aHoward Hughes Medical Institute investigator.Eva Nogales works on structural and functional characterization of macromolecular complexes. Her lab uses electron microscopy, computational image analysis as well as functional biochemical assays to gain insights into function and regulation of the large biological assemblies.
----Biography
Eva Nogales obtained her BS degree in physics from the Universidad Autonoma de Madrid, Spain in 1988. She earned her PhD from from the University of Keele, U.K. in 1992 while working at the Synchrotron Radiation Source under the supervision of Joan Bordas.
During her post-doctoral work in the Ken Downing lab, Eva Nogales was the first to determine the atomic structure of
tubulin by electron crystallography [Nogales, E., Wolf, S. G. and Downing, K. H. Structure of the ab tubulin dimer by electron crystallography. "Nature", 1998, 391, 199-203.] . She now continues to studymicrotubule dynamics in her own [http://cryoem.berkeley.edu/ laboratory] . [Nogales, E., Wang. H-W. Structural intermediates in microtubule assembly and disassembly: how and why? "Curr. Opin. Cell. Biol." 2006 ;18(2):179-84.] . In addition to microtubules, Dr. Nogales explores the structural and functional aspects of large macromolecular assemblies such as eukaryotic transcription and translation initiation complexes.Awards and honors
Dr. Nogales is a recipient of several awards including Early Career Award by the American Society for Cell Biology (2005), and the Chabot Science Award for Excellence (2006).
Personal information
Eva Nogales is married to Howard Padmore and they have two children.
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