Plasmodium yoelii

"Plasmodium achiotense" is a parasite of the genus "Plasmodium" subgenus "Vinckeia".

Like all "Plasmodium" species "P. yoelii" has both vertebrate and insect hosts. The vertebrate hosts for this parasite are mammals.

Taxobox
color = khaki
name = "Plasmodium yoelii"
image_caption =


image_width =
regnum = Protista
phylum = Apicomplexa
classis = Aconoidasida
ordo = Haemosporida
familia = Plasmodiidae
genus = "Plasmodium"
species = "P. yoelii"
binomial = "Plasmodium yoelii"

Description

This species was described in 1968 by Landau, Michel and Adam.

Geographical occurrence

Clinical features and host pathology

This is a species that infects rodents.

Notes

Its most notable feature is that it is used in the laboratory to infect mice, as a model of human malaria, particularly with respect to the immune response.

It is advantageous to have a whole-animal model of malaria because often it is difficult to know which factors to study "in vitro", particularly in a complex system like the immune system. Moreover, for many experiments it is not ethical or practical to use humans.

One of the special things about this particular model is that is has two strains with vastly different pathogenicity. These are generally referred to as the "lethal" and "non-lethal" strains of the species. Comparison of these two strains can be used to deduce which factors may contribute to more serious malaria infections in humans.

References