Aquaporin 3

Aquaporin 3

protein
Name=aquaporin 3 (Gill blood group)
caption=


width=
HGNCid=636
Symbol=AQP3
AltSymbols=
EntrezGene=360
OMIM=600170
RefSeq=NM_004925
UniProt=Q92482
PDB=
ECnumber=
Chromosome=9
Arm=p
Band=13
LocusSupplementaryData=

Aquaporin 3 is found in the basolateral cell membrane of principal collecting duct cells and provide a pathway for water to exit these cells.cite journal | author = Sasaki S, Ishibashi K, Marumo F | title = Aquaporin-2 and -3: representatives of two subgroups of the aquaporin family colocalized in the kidney collecting duct | journal = Annu. Rev. Physiol. | volume = 60 | issue = | pages = 199–220 | year = 1998 | pmid = 9558461 | doi = 10.1146/annurev.physiol.60.1.199 | issn = ] In kidney, AQP3 gene expression is not regulated by vasopressin (ADH).cite journal | author = Dibas AI, Mia AJ, Yorio T | title = Aquaporins (water channels): role in vasopressin-activated water transport | journal = Proc. Soc. Exp. Biol. Med. | volume = 219 | issue = 3 | pages = 183–99 | year = 1998 | pmid = 9824541 | doi = | issn = | url = http://www.ebmonline.org/cgi/content/abstract/219/3/183 ] This protein is also a determinant for the GIL blood group system.cite journal | author = Roudier N, Ripoche P, Gane P, Le Pennec PY, Daniels G, Cartron JP, Bailly P | title = AQP3 deficiency in humans and the molecular basis of a novel blood group system, GIL | journal = J. Biol. Chem. | volume = 277 | issue = 48 | pages = 45854–9 | year = 2002 | pmid = 12239222 | doi = 10.1074/jbc.M208999200 | issn = ]

ee also

* Aquaporin

References

External links

* [http://www.ncbi.nlm.nih.gov/projects/mhc/xslcgi.fcgi?cmd=bgmut/systems_info&system=gil GIL blood group system at BGMUT] Blood Group Antigen Gene Mutation Database at NCBI, NIH


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