ESC

ESC can refer to:
* As an abbreviation
** Ecole Supérieure de Commerce a business school in the French system of "Grandes Ecoles", such as Ecole Supérieure de Commerce de Rennes
** The Edmonton Ski Club
** Electric Sheep Company.
** Electronic Stability Control.
** Electronic Systems Center.
** Electronic speed control.
** Embryonic stem cell.
** Empire State College.
** Empire Supporters Club.
** Engineering Student Council (UP).
** English Subject Centre.
** Escanaba, Michigan : the IATA for Delta County Airport.
** Essential Services Commission.
** Eurobodalla Shire Council.
** European Steady Cycle
** European emission standards
** European Students Conference the largest biomedical scientific conference in Europe entirely run by students.
** Sustainment Command(Expeditionary)
** The European Space Camp.
** The European Super Cup.
** Eurovision Song Contest.
** ESC Reed relay-based telephone switching system of Stromberg-Carlson.
** European Shooting Confederation
** Essex Senior Cup a football competition in Essex, England,

* As a shortened version of the word "escape"
** The Esc key on a keyboard.
** The escape character in the C0 control code set.

* Others
** Esc Entertainment, a visual effects company who was responsible for much of the computer-generated imagery rendering for the Matrix Reloaded and Matrix Revolutions.
** A son of the 5th century king Hengest, see Oisc of Kent.
** A software development company located in Istanbul/ Turkey.