Bis-tris methane

Bis-tris methane

Chembox new
Name = Bis-tris methane
ImageFile = Bis-tris methane-Line-Structure.png ImageName = Bis-tris methane
IUPACName = 2- [Bis-(2-hydroxyethyl)-amino] -
2-hydroxymethyl-propane-1,3-diol
OtherNames =Bis-tris
Bis-(2-hydroxy-ethyl)-
amino-tris(hydroxymethyl)-methane
2,2-Bis(hydroxymethyl)-
2,2,2-nitrilotriethanol
Section1 = Chembox Identifiers
CASNo = 6976-37-0
SMILES = OCC(CO)(N(CCO)CCO)CO
RTECS = TY2900000
Section2 = Chembox Properties
Formula = C8H19NO5

MolarMass = 209.2418 g/mol
Appearance = white crystalline powder
Density = ? g/l, solid (25°C)
Solubility = 67? g/100 ml (20°C)
MeltingPt = 102-106°C (375-379K)
BoilingPt = (?K)
pKa = 5.80-7.30 @25°C
Section7 = Chembox Hazards
ExternalMSDS = [http://www.sigmaaldrich.com/cgi-bin/hsrun/Suite7/Suite/HAHTpage/Suite.HsSigmaAdvancedSearch.formAction External MSDS]
MainHazards = Irritant.
NFPA-H = 2
NFPA-F =
NFPA-R =
FlashPt = Non-flammable.
RPhrases = R36, R37, R38.
SPhrases = S26, S36.

Bis-tris is an abbreviation of the trivial name (Bis(2-hydroxyethyl)-imino-tris(hydroxymethyl)-methane) for 2- [Bis(2-hydroxyethyl)imino] -2-(hydroxymethyl)-1,3-propanediol. It is generally used as a buffering agent in biochemistry. Bis-tris is an organic tertiary amine with labile protons having a pKa of 6.46 at 25°C. It is an effective buffer between the pH 5.8 and 7.3.

ee also

*Bis-tris propane
*Tris
*Tricine

References


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