Impaired fasting glycaemia

Impaired fasting glycaemia (IFG) is a pre-diabetic state of dysglycemia, associated with insulin resistance and increased risk of cardiovascular pathology, although of lesser risk than Impaired glucose tolerance (IGT). IFG often progresses to type 2 diabetes mellitus, a recent study citing the average time for progression as less than three years. [cite journal |author=Nichols GA, Hillier TA, Brown JB| title=Progression From Newly Acquired Impaired Fasting Glusose to Type 2 Diabetes |journal=Diabetes Care |volume=30 |pages=228–233 |year=2007 |url=http://care.diabetesjournals.org/cgi/content/full/30/2/228| doi=10.2337/dc06-1392| pmid=17259486] IFG is also a risk factor for mortality.cite journal |author=Barr EL, Zimmet PZ, Welborn TA, "et al" |title=Risk of cardiovascular and all-cause mortality in individuals with diabetes mellitus, impaired fasting glucose, and impaired glucose tolerance: the Australian Diabetes, Obesity, and Lifestyle Study (AusDiab) |journal=Circulation |volume=116 |issue=2 |pages=151–7 |year=2007 |pmid=17576864 |doi=10.1161/CIRCULATIONAHA.106.685628]

It is characterised by an intermediately raised fasting glucose level, but less than would qualify for type 2 diabetes mellitus. On challenging with an oral glucose tolerance test, normal blood glucose levels are maintained after 2 hours, unlike IGT.

Criteria

* fasting glucose level > 5.6 mmol/l (100 mg/dl) and < 6.9 mmol/l (125mg/dl)..cite web |url=http://www.who.int/diabetes/publications/en/ |author=World Health Organization | title= Definition, diagnosis and classification of diabetes mellitus and its complications: Report of a WHO Consultation. Part 1. Diagnosis and classification of diabetes mellitus |accessdate=2007-05-29 |format= |work=] cite journal |author= |title=Diagnosis and classification of diabetes mellitus |journal=Diabetes Care |volume=28 Suppl 1 |issue= |pages=S37–42 |year=2005 |pmid=15618111 |doi=]

References

ee also

* Impaired glucose tolerance
* Glucose tolerance test