- Quassin
Chembox new
Name = Quassin
ImageFile = Quassin.png
ImageName = (+)-Quassin
IUPACName = (3aS,6aR,7aS,8S,11aS,11bS,11cS)1,3a,4,5,6a,7,7a,8,11,11a,11b,11c-dodecahydro-2,10dimethoxy-3,8,11a,11c-tetramethyldibenzo [de,g] chromene1,5,11-trione
EINECS = 200-985-9
Section1 = Chembox Identifiers2
CASNo = 76-78-8
PubChem = 10971
SMILES = CC1C=C(C(=O)C2(C1CC3C4(C2C(=O)C(=C(C4CC(=O)O3)C)OC)C)C)OC
InChIKey = IOSXSVZRTUWBHC-LBTVDEKVBB
Section2 = Chembox Properties
Formula = C22H28O6
MolarMass = 388.454 g/mol
Appearance = White crystalline substance
MeltingPt = 200-222°C
BoilingPt = 586°C
Solubility = Insoluble
VaporPressure = 13 mmHg (@ 25°C)Quassin is a white bitter, crystalline substance extracted from the
quassia tree. It is the bitterest substance found in nature with a bitter threshold of 0.08ppm and it is 50 times more bitter thanquinine .Scientific Committee on Food [http://ec.europa.eu/food/fs/sc/scf/out134_en.pdf Opinion of the Scientific Committee on Food on quassin (expressed on 2 July 2002).] SCF/CS/FLAV/FLAVOUR/29 Final ]Quassin is used as a
medicine intraditional Chinese medicine .Extracts of the Bitter tree (or bitter wood) ("
Quassia amara " L. or "Picrasma excelsa ") are also used as additives insoft drink s.Scientific Committee on Food [http://ec.europa.eu/food/fs/sc/scf/out134_en.pdf Opinion of the Scientific Committee on Food on quassin (expressed on 2 July 2002).] SCF/CS/FLAV/FLAVOUR/29 Final ]Although its skeleton possesses 20 carbon atoms Quassin is not a
diterpene but atriterpene lactone , which derives fromeuphol by loss of 10 carbon atoms including C4.References
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