Adiposogenital dystrophy

Infobox_Disease
Name = PAGENAME


Caption =
DiseasesDB = 29318
ICD10 = ICD10|E|23|6|e|20
ICD9 = ICD9|253.8
ICDO =
OMIM =
MedlinePlus =
eMedicineSubj =
eMedicineTopic =
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Adiposogenital dystrophy is a medical condition.

Presentation

It is characterized by:
* Feminine obesity
* Growth retardation and retarded sexual development, atrophy or hypoplasia of the gonads, and altered secondary sex characteristics,
* headaches
* mental retardation, problems with vision
* polyuria, polydipsia.

It is usually associated with tumours of the hypothalamus, causing increased appetite and depressed secretion of gonadotropin. It seems to affect males mostly.

Many overweight children may appear to have the disorder because of the concurrence of obesity and retarded sexual development; these children have no endocrine disturbances, however, and they mature normally after delayed puberty.

ynonyms

It has several other names: [ [http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Froelich%27s%20Syndrome National Organisation for Rare Disorders - Froelich's syndrome] ]

* "Babinski-Fröhlich syndrome" [WhoNamedIt|synd|1792 - Babinski-Fröchlich syndrome] (named after Joseph Babinski [J. F. Babinski. Tumeur du corps pituitaire sans acromégalie et avec arrêt de développement des organes génitaux. Revue neurologique, Paris, 1900, 8: 531-535. ] and Alfred Fröhlich, [A. Fröhlich. Ein Fall von Tumor der Hypophysis cerebri ohne Akromegalie. Wiener klinische Rundschau, 1901, 15: 833-836; 906-908. ] but probably first described by Morgagni).Fact|date=November 2007 (It was given its name by Harvey Cushing.)cite journal |author=Zárate A, Saucedo R |title= [The adiposogenital distrophy or Frohlich syndrome and the beginning of the concept of neuroendocrinology] |language=Spanish; Castilian |journal=Gac Med Mex |volume=143 |issue=4 |pages=349–50 |year=2007 |pmid=17969845 |doi=]
* "Froelich's syndrome"
* "Frölich's Syndrome"
* "Hypothalamic Infantilism-Obesity"
* "Launois-Cleret Syndrome"
* "Sexual Infantilism"

ee also

* Prader-Willi syndrome, to which it might resemble. However, this is a genetic disorder.

References