Differin is a trade name for a medication for "acne vulgaris" made by Galderma Laboratories. Its active ingredient is adapalene.

It is available in a 45g tube in the United Kingdom and under the NDC 0299-5910-45 in the United States, as well as a 35g tube in Australia and a 30g tube in Argentina. It is available in either a gel or creme form. Both forms contain 0.1% adapalene, a retinoid-like compound, as the active ingredient, however a 0.2% product is approved for sale in New Zealand. In June 2007, a higher concentration Differin gel (Adapalene) 0.3% was approved for use in the United States.

Differin works by modulating skin cell differentiation and growth and therefore regulating oil production and reducing acne over a long period of time. It has both exfoliating and anti-inflammatory effects. Studies show it is most effective on noninflammatory acne.

This drug will give much better results if a benzoyl peroxide wash is used morning and night and benzoyl peroxide lotion is applied in the a.m only along with the differin used in the p.m.Fact|date=July 2008 However, unlike Retin-A, adapalene has also been shown to retain its efficacy when applied at the same time as benzoyl peroxide due to its more stable chemical structure.

Chemical Properties

The molecular formula is C28H28O3

Side Effects of Use

Some of the normal side effects of Differin includes(burning, scaling, dryness, and stinging)

if these side effects get worse you should see a doctor about continuing the use of this product.

ee also

*Tretinoin (Retin-A)
*Tazarotene (Tazorac)

External links

* [http://www.differin.com Official Homepage]
* [http://www.druglib.com/druginfo/differin/ Drug label and research]

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