Synulox

Synulox is a widely known brand name of Veterinary Antibiotic, used for treating infections mostly in the lungs, and nasal tract; and as a broad-spectrum antibiotic. The drug is a compound of amoxicillin and Clavulanic Acid. See also Co-amoxiclav.

NB - All quantities shown below are combined - i.e. 500mg = 400mg Amoxicillin and 100mg Clavulanic Acid.

Formulations

*500mg Bolus: Large film-coated tablets. For the treatment of enteritis and navel ill in calves.

*Intramammary Suspension: Synulox + Prednisolone for intra-mammary infusion. For the treatment of mastitis in lactating cows.

*Palatable Drops: A powder for reconstitution for oral administration. A broad-spectrum antibiotic for dogs and cats.

*Palatable Tablets: Available as 50mg, 250mg and 500mg for oral administration. A broad-spectrum antibiotic for dogs and cats.

*Synulox Ready-To-Use Injection: Multi-purpose injectable formulation, recommended for respiratory tract infections, soft tissue infections, metritis and mastitis in cattle; respiratory tract infections, colibacillosis and mastitis, metritis & agalactia in pigs; respiratory tract infections, urinary tract infections, skin and soft tissue infections in dogs and cats.

Bacterial Resistance

Bacterial antibiotic resistance is a growing problem in veterinary medicine. Clavulanic acid inactivates beta-lactamases which are a common resistance strategy in gram positive bacteria. Synulox is reported to be effective against clinical "Klebsiella" infections, but is not efficacious against "Pseudomonas" infections.

References

*NOAH Compendium of Data Sheets for Animal Medicines 2007
*Federation of Veterinarians in Europe Position Paper: "Antibiotic Resistance & Prudent Use of Antibiotics in Veterinary Medicine" No longer online