Physiome

Physiome

The physiome of an individual's or species'physiological state is the description of itsfunctional behavior. The physiome describes the physiological dynamics ofthe normal intact organism and is built upon information andstructure (genome, proteome, and morphome). The term comes from "physio-" (life) and "-ome" (as a whole). In its broadest terms, it should define relationships from genome to
organism and from functional behavior to gene regulation. In contextof the Physiome Project, it includes integrated models ofcomponents of organisms, such as particular organs or cellsystems, biochemical, or endocrine systems.

The Physiome Project is a worldwide effort to define the physiomethrough the development of databases and models which will facilitate theunderstanding of the integrative function of cells, organs, andorganisms. The project is focused on compiling and providing a centralrepository of databases, linking experimental information andcomputational models from many laboratories into a single,self-consistent framework. This coalescence of research effort willpromote comprehensive databases and an integrative, analytical approachto the study of medicine and physiology.

Research initiatives related to the Physiome include:

* [http://www.physiome.ox.ac.uk/ The Wellcome Trust Physiome Project]
* [http://www.physiome.org.nz/ The IUPS Physiome Project]
*The EuroPhysiome Initiative.
* [http://www.physiome.org The NSR Physiome Project]

See also

*List of omics topics in biology
*Virtual Physiological Human
*Physiomics
*Genome
*Human Genome Project
*Cytome
*Human cytome project

External links

* [http://www.physiome.org/Links/ Physiome] - Links
* [http://www.physiome.ox.ac.uk/ Wellcome Trust Heart Physiome Project] - Links
* [http://www.europhysiome.org Strategy for the European Physiome] - (STEP)
* [http://www.physiome.org/ NSR Physiome Project]
* [http://www.physiome.org.nz/ IUPS Physiome Project]
* [http://www.nrcam.uchc.edu/ National Resource for Cell Analysis and Modeling] - (NRCAM)
* [http://omics.org Omics.org] General Omics related information siteExemplary Physiome Projects
* [http://www.aneurist.org @neurIST - Integrated Biomedical Informatics for the Management of Cerebral Aneurysms]
* [http://www.livinghuman.org LHDL - The Living Human Digital Library]
* [http://www.vphop.eu VPHOP - The Osteoporotic Virtual Physiological Human]


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