- Banti's syndrome
Banti's syndrome (also known as Banti's disease) is a chronic congestive enlargement of the
spleen [DorlandsDict|nine/000950693|Banti disease] resulting in premature destruction of thered blood cell s by the spleen. However, the term Banti's syndrome is a term that was used "in the past" (but isn't any longer) to describe patients withsplenomegaly ,hypersplenism andportal hypertension withoutcirrhosis and without occlusion of the portal venous system. [ [http://www.parkhurstexchange.com/qa/A.php?q=/qa/Gastroenterology/1997-02-26.qa Parkhurst Exchange Q & A] ]It is named for
Guido Banti . [WhoNamedIt|synd|475]Pathogenesis
The basic pathology is some kind of obstructive pathology in the portal,
hepatic orsplenic vein that causes obstruction ofvenous blood flow from the spleen towards the heart. The cause of such obstruction may be abnormalities present at birth (congenital) of certain veins, blood clots, or various underlying disorders causinginflammation and obstruction of veins (vascular obstruction) of the liver.Clinical presentation
Enlargement of spleen,
ascites ,jaundice , and the result of destruction of various blood cells by spleen -anemia ,leukopenia ,thrombocytopenia ,gastrointestinal tract bleeding - may constitute the presenting symptoms.External links
* [http://www.webmd.com/hw/hepatitis/nord722.asp WebMD article]
* [http://medical-dictionary.thefreedictionary.com/Banti's+syndrome Free Dictionary article]
* [http://www.pubmedcentral.com/articlerender.fcgi?artid=424896 1937 article in The Journal of Clinical Investigation]Organization
Organizations related to Banti's syndrome are:
* [http://www.liverfoundation.org American Liver Foundation]
* [http://www.niddk.nih.gov NIH/National Digestive Diseases Information Clearinghouse]Notes
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