MN gene

MN gene

The MN blood group in humans is under the control of a pair of co-dominant alleles, LMand LN.Most people in the Eskimo population are M/M, while this genotype is rare among Aborigines. In fact, they tend to possess the opposite genotype (N/N).

The MN blood group system is under the control of an autosomal locus found on chromosome 4 out of 23, with two alleles designated LM and LN. The bloodtype is due to a glycoprotein present on the surface of red blood cells, which behaves as a native antigen. Phenotypic expression at this locus is codominant because an individual may exhibit either one or both antigenic substances. Frequencies of the two alleles vary widely among human populations.

References

* http://www.mun.ca/biology/scarr/MN_bloodgroup.html


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