P11 protein

P11 protein

p11 is a protein found in the brain of humans and other mammals which has been implicated in the regulation of mood. A mouse study from 2006 found that low levels of p11 are likely to prevent the raising of serotonin levels from immediately curing clinical depression. The protein is thus a strong candidate target molecule for new antidepressant drugs.

ee also

*Biochemistry
*Neuroscience

References

*Svenningsson P, Chergui K, Rachleff I, Flajolet M, Zhang X, Yacoubi ME, Vaugeois JM, Nomikos GG, Greengard P. "Alterations in 5-HT1B receptor function by p11 in depression-like states". "Science" 2006;311(5757):77–80. PMID 16400147

External links

* [http://www.npr.org/templates/story/story.php?storyId=5133423 Associated story] on U.S. National Public Radio


Wikimedia Foundation. 2010.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • P11 — Contents 1 In government and politics 2 In military 3 In science and academia …   Wikipedia

  • Steroidogenic acute regulatory protein — protein Name=steroidogenic acute regulatory proteinth caption= width= HGNCid=11359 Symbol=StAR AltSymbols= EntrezGene=6770 OMIM=600617 RefSeq=NM 000349 UniProt=P49675 PDB= ECnumber= Chromosome=8 Arm=p Band=11.2 LocusSupplementaryData=The… …   Wikipedia

  • Surfactant protein B — protein Name=surfactant, pulmonary associated protein B caption= width= HGNCid=10801 Symbol=SFTPB AltSymbols=SFTP3 EntrezGene=6439 OMIM=178640 RefSeq=NM 000542 UniProt=P07988 PDB= ECnumber= Chromosome=2 Arm=p Band=12 LocusSupplementaryData=… …   Wikipedia

  • Pseudomonas sRNA P11 — is a ncRNA that was predicted using bioinformatic tools in the genome of the opportunistic pathogen Pseudomonas aeruginosa and its expression verified by northern blot analysis cite journal |author=Livny J, Brencic A, Lory S, Waldor MK… …   Wikipedia

  • Secreted frizzled-related protein 1 — The Secreted frizzled related protein (SFRP) family consists of five secreted glycoproteins in humans ( 300 amino acids in length) that act as extracellular signaling ligands. Each SFRP contains a cysteine rich domain (CRD) that shares 30 50%… …   Wikipedia

  • Pulmonary surfactant-associated protein B — Surfactant, pulmonary associated protein B, also known as SFTPB, is a human gene.cite web | title = Entrez Gene: SFTPB surfactant, pulmonary associated protein B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • Forkhead-Box-Protein A2 — Foxa2 Masse/Länge Primärstruktur 463 bzw. 457 Aminosäuren …   Deutsch Wikipedia

  • DNA damage-binding protein — damage specific DNA binding protein 1, 127kDa Identifiers Symbol DDB1 Alt. symbols XPE Entrez 1642 …   Wikipedia

  • Forkhead-Box-Protein O3 — Masse/Länge Primärstruktur 673 Aminosäuren …   Deutsch Wikipedia

  • S100A10 — S100 calcium binding protein A10 Crystallographic structure of the p11 protein dimer (cyan and green) complexed with the N terminus of annexin II (magenta) based on the PDB …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”