- Icaridin
Chembox new
Name = Icaridin
ImageFile = Picaridin.png
ImageName = Picaridin
IUPACName = 1-piperidinecarboxylic acid2-(2-hydroxyethyl)-1-­methylpropylester
PubChem=125098
Section1 = Chembox Identifiers
CASNo = 119515-38-7
SMILES = CCC(C)OC(=O)N1CCCCC1CCO
Section2 = Chembox Properties
Formula = C12H23NO3
MolarMass = 229.3 g/mol
Density =
BoilingPt = 296 °CIcaridin, also known as picaridine, KBR 3023, under the
INCI name hydroxyethyl isobutyl piperidine carboxylate, and under the old trade name Bayrepel and the current trade name Saltidin, is aninsect repellent . It has a broad efficacy against different insects and is almost colorless and odorless.The name "picaridin" was proposed as an
International Nonproprietary Name (INN) to theWorld Health Organization (WHO), but the official name that has been approved by theWHO is "icaridin". The compound was developed by the German chemical companyBayer and was given the name "Bayrepel". In 2005,LANXESS AG , and its subsidiarySaltigo GmbH were spun-off of Bayer [ [http://www.azom.com/News.asp?NewsID=2476 Bayer completes spin off of Lanxess AG] ] and the compounds was renamed "Saltidin" in 2008 [ [http://pubs.acs.org/cen/news/86/i20/8620news4.html C&EN News: Saltigo renames insect repellant] ] .Empirical findings
Icaridin has been reported to be as effective as
DEET without the irritation associated with DEET.Journal of Drugs and Dermatology (Jan-Feb 2004)] According to theWHO , icaridin “demonstrates excellent repellent properties comparable to, and often superior to, those of the standard DEET.” In the United States, theCenters for Disease Control and Prevention recommends using repellants based on icaridin,DEET , or oil oflemon eucalyptus (which may require more applications [ [http://www.thebostonchannel.com/health/4445009/detail.html CDC Approves New Weapons Against West Nile Virus] . WCVB TV, 3 May 2005.] ), for effective protection againstmosquito es that carry theWest Nile virus ,Eastern Equine Encephalitis and other illnesses.Unlike DEET, icaridin does not dissolve plastics. [ [http://www.picaridin.com/science.htm Picaridin] ]
Chemistry
The
INCI name for icaridin is "hydroxyethyl isobutyl piperidine carboxylate" [ [http://www.who.int/whopes/quality/en/Icaridin_spec_eval_Oct_2004.pdf WHO Specifications and evaluations for public health pesticides: Icaridin] ] . This chemical name name is wrong as icaridin it is an "sec"-butyl ester, not an "isobutyl" ester. Icaridin contains the substructure R2N-C(=O)-O-R, formally making it a substitutedcarbamate .See also
*
Insect repellent
*DEET References
External links
* [http://www.saltidin.com/ Saltidin]
* [http://www.findarticles.com/p/articles/mi_m0PDG/is_1_3/ai_113650073 Article from Journal of Drugs and Dermatology]
* [http://www.epa.gov/opprd001/factsheets/picaridin.pdf EPA fact sheet]
* [http://www.saltigo.com/ Saltigo]
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