Chembox new
Name = Icaridin
ImageFile = Picaridin.png ImageName = Picaridin
IUPACName = 1-piperidinecarboxylic acid2-(2-hydroxyethyl)-1-­methylpropylester
PubChem=125098
Section1 = Chembox Identifiers
CASNo = 119515-38-7
SMILES = CCC(C)OC(=O)N1CCCCC1CCO
Section2 = Chembox Properties
Formula = C12H23NO3
MolarMass = 229.3 g/mol
Density =
BoilingPt = 296 °C
Icaridin, also known as picaridine, KBR 3023, under the INCI name hydroxyethyl isobutyl piperidine carboxylate, and under the old trade name Bayrepel and the current trade name Saltidin, is an insect repellent. It has a broad efficacy against different insects and is almost colorless and odorless.
The name "picaridin" was proposed as an International Nonproprietary Name (INN) to the World Health Organization (WHO), but the official name that has been approved by the WHO is "icaridin". The compound was developed by the German chemical company Bayer and was given the name "Bayrepel". In 2005, LANXESS AG, and its subsidiary Saltigo GmbH were spun-off of Bayer [ [http://www.azom.com/News.asp?NewsID=2476 Bayer completes spin off of Lanxess AG] ] and the compounds was renamed "Saltidin" in 2008 [ [http://pubs.acs.org/cen/news/86/i20/8620news4.html C&EN News: Saltigo renames insect repellant] ] .
Empirical findings
Icaridin has been reported to be as effective as DEET without the irritation associated with DEET.[Journal of Drugs and Dermatology (Jan-Feb 2004)] According to the WHO, icaridin “demonstrates excellent repellent properties comparable to, and often superior to, those of the standard DEET.” In the United States, the Centers for Disease Control and Prevention recommends using repellants based on icaridin, DEET, or oil of lemon eucalyptus (which may require more applications [ [http://www.thebostonchannel.com/health/4445009/detail.html CDC Approves New Weapons Against West Nile Virus] . WCVB TV, 3 May 2005.] ), for effective protection against mosquitoes that carry the West Nile virus, Eastern Equine Encephalitis and other illnesses.]Unlike DEET, icaridin does not dissolve plastics. [ [http://www.picaridin.com/science.htm Picaridin] ]
Chemistry
The INCI name for icaridin is "hydroxyethyl isobutyl piperidine carboxylate" [ [http://www.who.int/whopes/quality/en/Icaridin_spec_eval_Oct_2004.pdf WHO Specifications and evaluations for public health pesticides: Icaridin] ] . This chemical name name is wrong as icaridin it is an "sec"-butyl ester, not an "isobutyl" ester. Icaridin contains the substructure R2N-C(=O)-O-R, formally making it a substituted carbamate.
See also
* Insect repellent
* DEET
References
External links
* [http://www.saltidin.com/ Saltidin]
* [http://www.findarticles.com/p/articles/mi_m0PDG/is_1_3/ai_113650073 Article from Journal of Drugs and Dermatology]
* [http://www.epa.gov/opprd001/factsheets/picaridin.pdf EPA fact sheet]
* [http://www.saltigo.com/ Saltigo]
