Isopentenyl pyrophosphate
- Isopentenyl pyrophosphate
Chembox new
ImageFile=IPP.pngImageSize=
IUPACName=(hydroxy-(3-methylbut-3-enoxy) phosphoryl)oxyphosphonic acid
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Section1= Chembox Identifiers
CASNo=358-71-4
PubChem=1195
SMILES=CC(=C)CCOP(=O)(O)OP(=O)(O)O
MeSHName=isopentenyl+pyrophosphate
Section2= Chembox Properties
Formula=C5H12O7P2
MolarMass=246.092
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Section3= Chembox Hazards
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Isopentenyl pyrophosphate (IPP) is an intermediate in the classical, HMG-CoA reductase pathway used by organisms in the biosynthesis of terpenes and terpenoids. IPP is formed from acetyl-CoA via mevalonic acid. IPP can then be isomerized to dimethylallyl pyrophosphate by the enzyme isopentenyl pyrophosphate isomerase.
Alternatively, IPP can be synthesized via the alternative, non-mevalonate pathway of isoprenoid biosynthesis instead where it is formed from ("E")-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMB-PP) by the enzyme HMB-PP reductase (LytB, IspH). The non-mevalonate pathway is utilized by many bacteria, apicomplexan protozoa such as malaria parasites, and the plastids of higher plants.
ee also
* Dimethylallyltranstransferase
External links
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