Hematein

Hematein

Chembox new
ImageFile=Haematein.pngImageSize=
IUPACName=3,4,6a,10-Tetrahydroxy-6,7-dihydroindeno [2,1-c] chromen-9-one
OtherNames=
Section1= Chembox Identifiers
CASNo=475-25-2
PubChem=10138
SMILES=C1C2=CC(=O)C(=CC2=C3C1(COC4=C3C=CC(=C4O)O)O)O
MeSHName=Hematein

Section2= Chembox Properties
Formula=C16H12O6
MolarMass=300.26 g/mol
Appearance=
Density=
MeltingPt=
BoilingPt=
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Section3= Chembox Hazards
MainHazards=
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Autoignition=

Hematein or haematin is an oxidized derivative of haematoxylin, used in staining.

Hematein exhibits indicator-like properties, being blue and less soluble in aqueous alkaline conditions, and red and more soluble in alcoholic acidic conditions. In acidic conditions, hematein binds to lysine residues of nuclear histones by linkage via a metallic ion mordant like Fe(III) or Al(III) salts, forming lakes or colored complexes (dye-mordant-tissue complexes), the color of which will depend on the salt used. Aluminium salt lakes are usually colored blue white while ferric salt lakes are colored blue-black.

Structures that stain with hematein are called basophilic. The basophilic structures are usually the ones containing nucleic acids, such as the ribosomes and the chromatin-rich cell nucleus, and the cytoplasmatic regions rich in RNA.

References


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  • Hematein — Hem a*te in, n. [Gr. ?, ?, blood.] (Chem.) A reddish brown or violet crystalline substance, {C16H12O6}, got from hematoxylin by partial oxidation, and regarded as analogous to the phthaleins. [1913 Webster] …   The Collaborative International Dictionary of English

  • hematein — [hē΄mə tē′in, hem΄ətē′in] n. [< HEMAT(OXYLIN) + IN1] a reddish brown, crystalline dye, C16H12O6, obtained from logwood extracts by oxidation and used as a stain and indicator …   English World dictionary

  • hematein — /hee meuh tee in, hem euh , hee meuh teen , hem euh /, n. a reddish brown, crystalline, slightly water soluble solid, C16H12O6, obtained from logwood: used chiefly as a stain in microscopy. [var. of HEMATIN] * * * …   Universalium

  • hematein — noun An oxidized derivative of haematoxylin, used in staining …   Wiktionary

  • hematein — An oxidation product of hematoxylin. Baker acid h. an acidic solution of oxidized hematoxylin used on frozen sections for staining phospholipids. * * * he·ma·tein or chiefly Brit hae·ma·tein .hē mə tē ən, hē mə .tēn n a reddish br …   Medical dictionary

  • hematein — n. chemical substance used as a stain in microscopy …   English contemporary dictionary

  • hematein — he·ma·te·in …   English syllables

  • hematein — he•ma•te•in [[t]ˌhi məˈti ɪn[/t]] n. chem. a reddish brown, crystalline solid, C16H12O6, obtained from logwood: used chiefly as a stain in microscopy • Etymology: 1930–35; var. of hematin …   From formal English to slang

  • hematein — ˌhēməˈtēə̇n, ˌhem noun ( s) Etymology: International Scientific Vocabulary hemat + ein : a reddish brown crystalline phenolic quinonoid compound C16H12O6 constituting the essential dye in logwood extracts see hematoxylin …   Useful english dictionary

  • C16H12O6 — Hematein Hem a*te in, n. [Gr. ?, ?, blood.] (Chem.) A reddish brown or violet crystalline substance, {C16H12O6}, got from hematoxylin by partial oxidation, and regarded as analogous to the phthaleins. [1913 Webster] …   The Collaborative International Dictionary of English

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