Lymphangiosarcoma

Lymphangiosarcoma

DiseaseDisorder infobox
Name = PAGENAME
ICD10 =
ICD9 =
ICDO = 9170/3


Caption =
OMIM =
OMIM_mult =
MedlinePlus =
eMedicineSubj =
eMedicineTopic =
DiseasesDB = 29095
MeshID = D008204

Lymphangiosarcoma is a rare malignant tumor which occurs in long-standing cases of Primary or Secondary Lymphedema. It involves either the upper or lower lymphedemateous extremities but is most common in upper extremities.

Presentation

The sarcoma first appears as a bruise mark, a purplish discolorization or a tender skin nodule in the extremity, typically on the anterior surface. It progresses to an ulcer with crusting, and finally to an extensive necrosis involving the skin and subcutaneous tissue. It metastasizes quickly.

Causes

It was previously a relatively common complication of the massive lymphedema of the arm which followed removal of axillary (arm pit) lymph nodes and lymphatic channels as part of the classical Halstedian radical mastectomy, as a treatment for breast cancer. The classical radical mastectomy was abandoned in most areas of the world in the late 1960's to early 1970's, being replaced by the much more conservative modified radical mastectomy and, more recently, by segmental breast tissue excision and radiation therapy. Because of this change in clinical practice lymphedema is now a rarity following breast cancer treatment - and post-mastectomy lymphangiosarcoma is now vanishingly rare. When it occurs following mastectomy it is known as Stewart-Treves syndrome (which can be both lymphangiosarcoma and hemangiosarcoma following mastectomy).

References

*Cancer: Principles & Practice of Oncology, 6th Edition, DeVita, Hellman and Rosenberg, p. 1853

ee also

* Lymphangioma

External links

*


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Look at other dictionaries:

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  • lymphangiosarcoma — n. a rare malignant tumour of the lymphatic vessels. It is most commonly seen in the chronically swollen (oedematous) arms of women who have had a mastectomy for breast cancer and may be induced by radiation …   The new mediacal dictionary

  • lymphangiosarcoma — A type of cancer that begins in the cells that line lymph vessels …   English dictionary of cancer terms

  • lymphangiosarcoma — …   Useful english dictionary

  • Лимфангиосаркома (Lymphangiosarcoma) — крайне редко встречающаяся злокачественная опухоль лимфатических сосудов. Обычно она развивается у женщин, перенесших мастэктомию по поводу рака молочной железы, и проявляется в виде постоянной припухлости подмышечных впадин. Источник:… …   Медицинские термины

  • лимфангиосаркома — (lymphangiosarcoma; лимфангио + саркома; название злокачественных опухолей, развивающихся из элементов стенки лимфатических сосудов …   Большой медицинский словарь

  • Лимфангиосарко́ма — (lymphangiosarcoma; Лимфангио + Саркома, син. лимфангиобластома) общее название злокачественных опухолей, развивающихся из элементов стенки лимфатических сосудов …   Медицинская энциклопедия

  • Stewart-Treves syndrome — lymphangiosarcoma which occurs as a late complication of severe lymphedema of the arm following excision of lymph nodes, usually associated with radical mastectomy …   Medical dictionary

  • ЛИМФАНГИОСАРКОМА — (lymphangiosarcoma) крайне редко встречающаяся злокачественная опухоль лимфатических сосудов. Обычно она развивается у женщин, перенесших мастэктомию по поводу рака молочной железы, и проявляется в виде постоянной припухлости подмышечных впадин …   Толковый словарь по медицине

  • Lymphedema — Classification and external resources ICD 10 I89.0, I97.2, Q82.0 …   Wikipedia

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