Polysorbate

Polysorbate

Polysorbates are a class of emulsifiers used in some pharmaceuticals and food preparation. They are often used in cosmetics to solubilize essential oils into water-based products. Polysorbates are oily liquids derived from PEG-ylated sorbitan (a derivative of sorbitol) esterified with fatty acids. Surfactants that are esters of plain (non-PEG-ylated) sorbitan with fatty acids are usually referred to by the name Span.

Examples

*Polysorbate 20 (Tween 20 or polyoxyethylene (20) sorbitan monolaurate)
*Polysorbate 40 (Tween 40 or polyoxyethylene (20) sorbitan monopalmitate)
*Polysorbate 60 (Tween 60 or polyoxyethylene (20) sorbitan monostearate)
*Polysorbate 80 (Tween 80 or polyoxyethylene (20) sorbitan monooleate)

The number 20 following the "polyoxyethylene" part refers to the total number of oxyethylene -(CH2CH2O)- groups found in the molecule. The number following the "polysorbate" part is related to the type of fatty acid associated with the polyoxyethylene sorbitan part of the molecule. Monolaurate is indicated by 20, monopalmitate is indicated by 40, monostearate by 60 and monooleate by 80. The same numbering is followed in their Span equivalents (Span 20, Span 40, Span 60 and Span 80).

ee also

*Span 20 (Sorbitan monolaurate)
*Span 40 (Sorbitan monopalmitate)
*Span 60 (Sorbitan monostearate)
*Span 65 (Sorbitan tristearate)
*Span 80 (Sorbitan monooleate)

External links

* [http://householdproducts.nlm.nih.gov/cgi-bin/household/brands?tbl=chem&id=1547 NIH PEG-60 (Polysorbate 60)] Household Products Database


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  • Polysorbate 20 — IUPAC name Polyoxyethylene (20) sorbitan monolaurate …   Wikipedia

  • Polysorbate — sind chemische Verbindungen, die durch Veretherung von Sorbitanfettsäureestern mit Polyethylenglycol entstehen. Sie sind grenzflächenaktiv und werden als Netzmittel oder Öl in Wasser Emulgatoren beispielsweise in Kosmetika, Arzneimitteln,… …   Deutsch Wikipedia

  • Polysorbate 80 — Chembox new Reference= [ Merck Index , 13th Edition, 7664.] Name = Polysorbate 80 ImageFile = Polysorbate 80.png ImageSize = 275px ImageName = IUPACName = Polyoxyethylene (20) sorbitan monooleate OtherNames = Tween 80 Section1 = Chembox… …   Wikipedia

  • polysorbate — noun Date: 1950 any of several emulsifiers used in the preparation of some pharmaceuticals or foods …   New Collegiate Dictionary

  • polysorbate — pol·y·sor·bate (pŏl ē sôrʹbāt ) n. Any of a class of emulsifiers used in food preparation and in some pharmaceuticals.   [poly + sorbate, salt or ester of sorbitol (sorbitol + ate2).] * * * …   Universalium

  • polysorbate — noun any of a class of emulsifiers used as food additives and in pharmaceutical preparations; they are derived from sorbitan (typically with three polyoxyethylene side chains) esterified with a fatty acid; they are mostly oily liquids, or soft… …   Wiktionary

  • polysorbate 80 — A mixture of polyoxethylene ethers of mixed partial oleic esters of sorbitol anhydrides; used as an emulsifier, as in the preparation of pharmacologic products …   Medical dictionary

  • polysorbate — poly·sor·bate .päl i sȯr .bāt n any of several emulsifiers used in the preparation of some pharmaceuticals and foods see TWEEN * * * poly·sor·bate (pol″e sorґbāt) a generic name for esters of sorbitol and its anhydrides condensed with …   Medical dictionary

  • polysorbate — poly·sorbate …   English syllables

  • polysorbate — ¦pälē, lə̇ˌ noun Etymology: poly + sorbate : any of several emulsifiers used in preparing some pharmaceuticals and foods …   Useful english dictionary

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