Rutin

Chembox new
Name = Rutin
ImageFile = Rutin.png ImageSize = 275px
ImageName = Rutin
IUPACName = 2-(3,4-dihydroxyphenyl)-
4,5-dihydroxy-3- [3,4,5-
trihydroxy-6- [(3,4,5-
trihydroxy-6-methyl-
oxan-2-yl)oxymethyl]
oxan-2-yl] oxy-chromen-
7-one
Section1 = Chembox Identifiers
CASNo = 153-18-4
SMILES = xxxxx
Section2 = Chembox Properties
Formula = C₂₇H₃₀O₁₆
MolarMass = 610.52 g/mol
Density = x.xxx g/cm³
MeltingPt =
BoilingPt =

Rutin, also called rutoside, quercetin-3-rutinoside and sophorin, is a citrus flavonoid glycoside found in buckwheat [cite journal
author=Kreft S, Knapp M, Kreft I
title=Extraction of rutin from buckwheat (Fagopyrum esculentum Moench) seeds and determination by capillary electrophoresis
journal=Journal of Agricultural and Food Chemistry
volume=47
issue=11
pages=4649–4652
date=November 1999
url=http://www.ncbi.nlm.nih.gov/pubmed/10552865
doi=10.1021/jf990186p] , the leaves and petioles of "Rheum" species, and the fruit of the Fava D'Anta tree (from Brazil), as well as other sources. Its name comes from the name of Ruta graveolens, a plant, that also contains rutin. Rutin is the glycoside between the flavonol quercetin and the disaccharide rutinose.

It can combine with cations, supplying nutrients from the soil to the cells in plants. In humans, it attaches to the iron ion Fe²⁺, preventing it from binding to hydrogen peroxide, which would otherwise create a highly-reactive free-radical that may damage cells. It is also an antioxidant, and therefore plays a role in inhibiting some cancers.

Rutin also strengthens the capillaries, and, therefore, can reduce the symptoms of haemophilia. It also may help to prevent a common unpleasant-looking venous edema of the legs. Rutin, as ferulic acid, can reduce the cytotoxicity of oxidized LDL cholesterol and lower the risk of heart disease.

Rutin has a veterinary use in the management of chylothorax in dogs and cats.

References