- Macrocytosis
Infobox_Disease
Name = Macrocytosis
Caption =
DiseasesDB = 7688
ICD10 = ICD10|D|75|8|d|70
ICD9 = ICD9|289.89
ICDO =
OMIM =
MedlinePlus =
eMedicineSubj = med
eMedicineTopic = 1381
MeshName =
MeshNumber =Macrocytosis is the enlargement of
red blood cell s with near-constanthaemoglobin concentration, and is defined by amean corpuscular volume (MCV) of greater than 100 femtolitres (the precise criterion varies between laboratories).Causes
Most commonly (especially when the increase in size is mild, and just above normal range) the etiology is
bone marrow dysplasia primary toalcohol abuse . Other causes may include:*
Megaloblastosis (Vitamin B12 orfolate deficiency; or DNA synthesis-inbiting drugs)
*hypothyroidism
*reticulocytosis (commonly fromhemolysis or a recent history ofblood loss ).
*liver disease
*myeloproliferative disease Complications
No complications arise from macrocytosis itself and a
prognosis will be determined from itsaetiology .
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