PAPLN

Papilin, proteoglycan-like sulfated glycoprotein
Identifiers
Symbols	PAPLN; DKFZp434F053; MGC50452
External IDs	MGI: 2386139 HomoloGene: 71541 GeneCards: PAPLN Gene
Gene Ontology Molecular function • metalloendopeptidase activity • serine-type endopeptidase inhibitor activity • zinc ion binding • peptidase inhibitor activity Cellular component • extracellular region • proteinaceous extracellular matrix Biological process • proteolysis • cell-cell adhesion Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	89932	170721
Ensembl	ENSG00000100767	ENSMUSG00000021223
UniProt	O95428	Q9EPX2
RefSeq (mRNA)	NM_173462	NM_130887
RefSeq (protein)	NP_775733	NP_570957
Location (UCSC)	Chr 14: 73.7 – 73.74 Mb	Chr 12: 85.1 – 85.13 Mb
PubMed search	[1]	[2]

Papilin is a protein that in humans is encoded by the PAPLN gene.^[1][2][3] Papilin is an extracellular matrix glycoprotein.

References

1. ^ "Entrez Gene: papilin". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=89932. 
2. ^ Kramerova IA, Kawaguchi N, Fessler LI, Nelson RE, Chen Y, Kramerov AA, Kusche-Gullberg M, Kramer JM, Ackley BD, Sieron AL, Prockop DJ, Fessler JH (December 2000). "Papilin in development; a pericellular protein with a homology to the ADAMTS metalloproteinases". Development 127 (24): 5475–85. PMID 11076767. 
3. ^ Apte SS (November 2009). "A disintegrin-like and metalloprotease (reprolysin-type) with thrombospondin type 1 motif (ADAMTS) superfamily: functions and mechanisms". J. Biol. Chem. 284 (46): 31493–7. doi:10.1074/jbc.R109.052340. PMC 2797218. PMID 19734141. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2797218. 

Further reading

• Rose JE, Behm FM, Drgon T, et al. (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2896464. 
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=403697. 
• Laje G, Allen AS, Akula N, et al. (2009). "Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients". Pharmacogenet. Genomics 19 (9): 666–74. doi:10.1097/FPC.0b013e32832e4bcd. PMC 2819190. PMID 19724244. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2819190. 
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1356129.