Oncocyte

Oncocyte
Oncocytes (left of image), as seen in a renal oncocytoma. H&E stain.

An oncocyte is an epithelial cell characterized by an excessive amount of mitochondria, resulting in an abundant acidophilic, granular cytoplasm. Oncocytes can be benign or can undergo malignant transformation.

Contents

Other names

Also known as:

  • Hurthle cell (thyroid gland only)
  • Oxyphilic cell,
  • Askanazy cell,
  • Apocrine metaplasia (breast gland only).

Etymology

Derived from the Greek root onco-, which means mass, bulk.

See also

  • Oncocytoma, a tumour composed of oncocytes, may be found as a less common salivary gland neoplasm also known as Oxyphilic Adenoma.
  • Renal oncocytoma, a kidney tumour composed of oncocytes.
  • Hurthle cell carcinoma, a variant of follicular thyroid carcinoma).

External links


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Look at other dictionaries:

  • oncocyte — oncocyte. См. онкоцит. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • oncocyte — noun A large, granular cell, having many mitochondria, found in salivary and certain endocrine glands See Also: oncocytoma‎ …   Wiktionary

  • oncocyte — A large, granular, acidophilic tumor cell containing numerous mitochondria; a neoplastic oxyphil cell. [onco + G. kytos, cell] * * * on·co·cyte also on·ko·cyte äŋ kō .sīt n an acidophilic granular cell esp. of the parotid gland * …   Medical dictionary

  • oncocyte — on·co·cyte …   English syllables

  • oncocyte — ˈäŋkōˌsīt noun ( s) Etymology: onco (I) + cyte 1. : an acidophilic granular cell especially of the parotid gland 2. : a tumor cell …   Useful english dictionary

  • онкоцит — oncocyte онкоцит. Отмирающая эпителиальная клетка, характеризующаяся крупным размером, набухшей цитоплазмой и пикнотическим ядром. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во… …   Молекулярная биология и генетика. Толковый словарь.

  • Mitochondrion — For the metal band, see Mitochondrion (band). Two mitochondria from mammalian lung tissue displaying their matrix and membranes as shown by electron microscopy …   Wikipedia

  • oncocytic — adjective Of or pertaining to an oncocyte or to oncocytoma …   Wiktionary

  • oncocytoma — A glandular tumor composed of large cells with cytoplasm that is granular and eosinophilic because of the presence of abundant mitochondria; occurs uncommonly in the kidney, salivary glands, and endocrine glands. SYN: oxyphil adenoma. [onco + G.… …   Medical dictionary

  • onkocyte — onkocyte, onkocytoma var of ONCOCYTE, ONCOCYTOMA …   Medical dictionary

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