Nucleobase Cation Symporter

Nucleobase Cation Symporter
Permease for cytosine/purines, uracil, thiamine, allantoin
Identifiers
Symbol Transp_cyt_pur
Pfam PF02133
InterPro IPR001248
TCDB 2.A.39
OPM family 67
OPM protein 2x79

The Nucleobase Cation Symporter-1 (NCS1) family consists of bacterial and yeast transporters for nucleobases including purines and pyrimidines. Members of this family possess twelve transmembrane a-helical spanners (TMSs). At least some of them have been shown to function in uptake by substrate:H+ symport mechanism. See also IPR012681 and IPR012732.