- Duffy binding proteins
-
Duffy binding domain crystal structure of eba-175 region ii (rii) crystallized in the presence of (alpha)2,3-sialyllactose Identifiers Symbol Duffy_binding Pfam PF05424 Pfam clan CL0195 InterPro IPR008602 Available protein structures: Pfam structures PDB RCSB PDB; PDBe PDBsum structure summary Duffy binding protein N terminal Identifiers Symbol DuffyBP_N Pfam PF12377 InterPro IPR021032 Available protein structures: Pfam structures PDB RCSB PDB; PDBe PDBsum structure summary In molecular biology, Duffy binding proteins are found in plasmodia. Plasmodium vivax and Plasmodium knowlesi merozoites invade Homo sapiens erythrocytes that express Duffy blood group surface determinants. The Duffy receptor family is localised in micronemes, an organelle found in all organisms of the phylum Apicomplexa.[1][2]
See also
- Genetic resistance to malaria
References
- ^ Adams JH, Hudson DE, Torii M, Ward GE, Wellems TE, Aikawa M, Miller LH (October 1990). "The Duffy receptor family of Plasmodium knowlesi is located within the micronemes of invasive malaria merozoites". Cell 63 (1): 141–53. doi:10.1016/0092-8674(90)90295-P. PMID 2170017.
- ^ Babaeekho, L.; Zakeri, S.; Djadid, N. D. (2009). "Genetic mapping of the duffy binding protein (DBP) ligand domain of Plasmodium vivax from unstable malaria region in the Middle East". The American journal of tropical medicine and hygiene 80 (1): 112–118. PMID 19141848.
This article includes text from the public domain Pfam and InterPro IPR008602
Categories:- Protein families
Wikimedia Foundation. 2010.