Differentiation-inducing factor

Differentiation-inducing factor

Differentiation-inducing factor (DIF) is one of a class of effector molecules that induce changes in cell chemistry, inhibiting growth and promoting differentiation of cell type. DIFs 1-3 are chlorinated hexaphenones (phenylalkan-1-ones, with chloro, hydroxy and methoxy substitution on the benzene ring), and have been isolated from Dictyostelium discoideum slime mold. DIFs have been of interest because of their tumor inhibiting properties. DIFs have also been used to help regulate plant growth.

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