DRB

DRB may refer to:

• Defence Research and Development Canada, the Canadian Defence Research Board
• Deutsche Reichsbahn, the German Imperial Railways or its wartime locomotive classes such as the DRB Class 50
• Deutscher Richterbund, the German Association of Judges
• 5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole, a chemical compound that inhibits gene transcription
• Digital Radio Broadcast Specialist, a professional title regulated by the Society of Broadcast Engineers
• Distributed Ruby
• DRB-HICOM, a Malaysian automotive company
• DRB Sports Cars, an Australian sports car company

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