DNase-Seq

DNase-Seq (DNase I hypersensitive sites sequencing) is a method in molecular biology used to identify the location of regulatory regions, based on the genome-wide sequencing of regions super sensitivity to cleavage by DNase I. ^[1] FAIRE-Seq is a successor of DNase-Seq for the genome-wide identification of accessible DNA regions in the genome.

References

1. ^ Crawford, GE; Holt, IE, Whittle, J, Webb, BD, Tai, D, Davis, S, Margulies, EH, Chen, Y, Bernat, JA, Ginsburg, D, Zhou, D, Luo, S, Vasicek, TJ, Daly, MJ, Wolfsberg, TG, Collins, FS (2006 Jan). "Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS).". Genome research 16 (1): 123–31. doi:10.1101/gr.4074106. PMC 1356136. PMID 16344561. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1356136.