DNASTAR

DNASTAR
DNASTAR, Inc.
Type Privately held company
Industry Bioinformatics Software
Founder(s) Dr. Fredrick Blattner, John Schroeder
Headquarters Madison, Wisconsin, United States
Area served Worldwide
Products Lasergene, ArrayStar, GenVision, SeqMan NGen
Website DNASTAR

DNASTAR is a bioinformatics company headquartered in Madison, WI that provides software for DNA sequence analysis and assembly, gene expression analysis, and genomic visualization.

Contents

History

DNASTAR was incorporated in 1984. Its primary software product, Lasergene, is usually used by molecular biology researchers for DNA and protein sequence assembly and analysis.[1]

The initial version of Lasergene was released in 1986, and it has since grown in its capabilities. The latest version, Lasergene 9.0, was released in April 2011.[2] The software supports virtual restriction enzyme cloning as well as TOPO cloning, and cloning using the Gateway technology. Lasergene has also added the functions to do BLAST and FASTA search and utilize multiple alignment methods including Clustal.

In June 2007, the company introduced its ArrayStar software for microarray gene expression analysis. The latest version of ArrayStar, version 4.0, which was released in 2010, included an optional module, QSeq, to allow scientists to visualize and analyze RNA-Seq and ChIP-Seq data using the same tools as are used for microarray gene expression.

In October 2007, the company introduced SeqMan NGen to assemble data from Next Generation sequencing platforms. When used along with Lasergene, SeqMan NGen permits researchers to assemble and analyze data from sequencing projects from both traditional and next generation sequencing technologies. Lasergene's use in Next Generation sequence assembly and analysis software was contributed as a chapter, written by company scientists, to the 2008 book Next Generation Genome Sequencing edited by Michael Janitz.

In 2008, DNASTAR was awarded a Reader's Choice Gold Award by Scientific Computing Magazine for the Lasergene sequence analysis software.[3]

The 2008 book Inventing Entrepreneurs: Technology Innovators and their Entrepreneurial Journey by Gerard George and Adam J. Bock includes DNASTAR as an example of an innovative and entrepreneurial success story.

Products

  • Lasergene is a suite of seven software modules used for molecular biology analysis including gene discovery, primer design, and sequence alignment.
  • ArrayStar is a package for statistical and graphical analysis of gene expression and regulation, using microarray and RNA-Seq data.
  • GenVision is a graphic design program for displaying biological data, it works both as a standalone application and as a plug-in for Adobe Illustrator.
  • SeqMan NGen is a sequence assembly program for large scale data from next generation sequencers such as Illumina and 454.

See also

References

  • Janitz, Michal (November 2008). Next-Generation Genome Sequencing: Towards Personalized Medicine. Wiley-VCH. ISBN 978-3-527-32090-5. 
  • Gerry, George; Adam Bock (January 2008). Inventing Entrepreneurs: Technology Innovators and their Entrepreneurial Journey. Prentice Hall. ISBN 978-0131574700. 

External links


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