Porokeratosis

Porokeratosis
Classification and external resources
A porokeratosis lesion in a patient with disseminated superficial actinic porokeratosis.
DiseasesDB	31356
eMedicine	article/1059123
MeSH	D017499

Porokeratosis is a specific disorder of keratinization that is characterized histologically by the presence of a cornoid lamella, a thin column of closely stacked, parakeratotic cells extending through the stratum corneum with a thin or absent granular layer.^[1]:532

Types

Porokeratosis may be divided into the following clinical types^[1]:532:

• Classic porokeratosis Mibelli
• Disseminated superficial actinic porokeratosis
• Disseminated superficial porokeratosis
• Porokeratosis palmaris et plantaris disseminata
• Linear porokeratosis
• Punctate porokeratosis

However, additional types have also been described^[2]:213,566:

• Porokeratosis plantaris discreta

Pathology

Micrograph of a case of porokeratosis showing a characteristic cornoid lamella (dark pink/red structure in the right/upper portion of the image). H&E stain.

Porokeratosis has a characteristic histomorphologic feature known as a cornoid lamella.

See also

• Skin lesion
• List of cutaneous conditions

References

1. ^ ^{a b} Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0071380760.
2. ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0721629210.

This Genodermatoses article is a stub. You can help Wikipedia by expanding it.v · Categories: Genodermatoses Genodermatoses stubs Wikimedia Foundation. 2010. Игры ⚽ Поможем написать реферат Basset horn Cornone di Blumone Look at other dictionaries: porokeratosis punctata palmaris et plantaris — punctate porokeratosis a skin disorder affecting the palms and soles and occurring during or after adolescence, characterized by tiny keratotic plugs that have elevated margins and do not enlarge; patients often exhibit either linear or Mibelli… …   Medical dictionary porokeratosis of Mibelli — the classic type of porokeratosis, a chronic, progressive, autosomal dominant type seen most often in males, usually first appearing in early childhood. Lesions are isolated, light brown papules with irregular shapes and a surrounding ridge that… …   Medical dictionary porokeratosis palmaris et plantaris disseminata — a variant of punctate porokeratosis characterized by small, superficial, slightly discolored lesions on the soles or palms or both, with gyrate or annular shapes; there may be hundreds of lesions, and they may later appear elsewhere on the body …   Medical dictionary porokeratosis ptychotropica — a rare verrucous variant of porokeratosis, affecting the gluteal cleft and characterized by pruritic, confluent plaques in the perianal region that extend symmetrically to the buttocks …   Medical dictionary porokeratosis — A rare dermatosis in which there is a thickening of the stratum corneum with an annular keratotic rim or cornoid lamella surrounding progressive centrifugal atrophy; cutaneous carcinoma has been reported to arise in the lesions. SYN: Mibelli… …   Medical dictionary porokeratosis — …   Useful english dictionary Plaque-type porokeratosis — Classification and external resources OMIM 175800 DiseasesDB 32454 MeSH …   Wikipedia Disseminated superficial actinic porokeratosis — Classification and external resources A porokeratosis lesion in a patient with disseminated superficial actinic porokeratosis. OMIM …   Wikipedia Disseminated superficial porokeratosis — is a more generalized processes than porokeratosis Mibelli, and involves mainly the exptremities in a bilateral, symmetric fashion.[1]:533 In about 50% of cases, skin lesions only develop in sun exposed areas, and this is referred to as… …   Wikipedia Craniosynostosis–anal anomalies–porokeratosis syndrome — Classification and external resources OMIM 603116 Craniosynostosis–anal anomalies–porokeratosis syndrome (also known as CAP syndrome ) is a cutaneous condition inherited in an autosomal recessive fashion.[1] …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”