Missouri Route 22

Route 22
Route information
Maintained by MoDOT
Length:	23 mi (37 km)
Existed:	1922 – present
Major junctions
East end:	Route 15 in Mexico
West end:	US 63/Route F south of Clark
Highway system
Missouri Highways Supplemental ← Route 21 Route 23 →

Route 22 is a highway in central Missouri. Its eastern terminus is at Route 15 in Mexico; its western terminus is at U.S. Route 63 south of Clark on the Randolph/Boone county line. Route 22 was one of the original 1922 state highways and originally had an eastern terminus at Route 9 (now U.S. Route 61) in Louisiana. This section was replaced by U.S. Route 54.