Myospherulosis

Myospherulosis

Placement of topical tetracycline in a petrolatum base into a surgical site may occasionally result in a unique foreign-body reaction, known as myospherulosis. The resultant histopathologic pattern is most unusual and initially was mistakenly thought to represent a previously undescribed endosporulating fungus.


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  • myospherulosis — A chronic granulomatous reaction to undetermined spherical structures frequently contained within a microscopic cyst; first reported in cystic lesions in skeletal muscle from eastern Africa and subsequently in nasal infections in the U.S. [myo +… …   Medical dictionary

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