Gefarnate

Gefarnate

Drugbox
IUPAC_name = [(2"E")-3,7-dimethylocta-2,6-dienyl] (4"E",8"E")-5,9,13-trimethyltetradeca-4,8,12-trienoate



width = 280
CAS_number = 51-77-4
ATC_prefix = A02
ATC_suffix = BX07
PubChem = 5282182
DrugBank =
C=27|H=44|O=2
molecular_weight = 400.637 g/mol
bioavailability =
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Gefarnate is a drug used for the treatment of gastric ulcers.cite journal |author=Ohta Y, Kobayashi T, Imai Y, Inui K, Yoshino J, Nakazawa S |title=Effect of gefarnate on acute gastric mucosal lesion progression in rats treated with compound 48/80, a mast cell degranulator, in comparison with that of teprenone |journal=Biol. Pharm. Bull. |volume=28 |issue=8 |pages=1424–30 |year=2005 |month=August |pmid=16079487 |doi= |url=http://joi.jlc.jst.go.jp/JST.JSTAGE/bpb/28.1424?from=PubMed]

It also has been proposed for use in the treatment of dry eye syndrome.cite journal |author=Peral A, Domínguez-Godínez CO, Carracedo G, Pintor J |title=Therapeutic targets in dry eye syndrome |journal=Drug News Perspect. |volume=21 |issue=3 |pages=166–76 |year=2008 |month=April |pmid=18560615 |doi= |url=] cite journal |author=Gipson IK, Hori Y, Argüeso P |title=Character of ocular surface mucins and their alteration in dry eye disease |journal=Ocul Surf |volume=2 |issue=2 |pages=131–48 |year=2004 |month=April |pmid=17216084 |doi= |url=http://www.theocularsurface.com/ArticlesV2N2-Gipson.htm]

References


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