Alarmone

Alarmone

articleissues
expert = Biochemistry
expand = September 2008
refimprove = September 2008
wikify = September 2008
technical = September 2008

Alarmone is an intracellular signal molecule that is produced due to harsh environmental factors. Alarmones are produced in high concentrations when harsh environmental factors occur in bacteria and plants, such as lack of amino acids to produce proteins. Stringent factors take uncharged tRNA and converts the tRNA to an alarmone. GDP will produce the archetypical alarmone (p)ppGpp (Guanosine 5' diphosphate 3' diphosphate) [http://www.nature.com/nrmicro/journal/v3/n2/glossary/nrmicro1084_glossary.html] and will decrease rRNA transcription.

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