- Euphorbia poisonii
Taxobox
name = "Euphorbia poisonii"
image_width = 250px
regnum =Plant ae
divisio = Magnoliophyta
classis =Magnoliopsida
ordo =Malpighiales
familia =Euphorbiaceae
genus =Euphorbia
species = "Euphorbia poisonii""Euphorbia poisonii", also known as "Euphorbia poissonii" [cite web|url=http://bodd.cf.ac.uk/BotDermFolder/BotDermE/EUPH-9.html|title=Euphorbiaceae|work=Botanical Dermatology Database|accessdate=2008-06-01] is a highly toxic and
succulent member of the large and variedSpurge genus of plants. It is native to northernNigeria , where local farmers extract itslatex for use as a pesticide, potent against any animal that enters the field. Its powerful and painful nature mandates fencing and clear marking of fields using the poison, but the produce is safe to eat as the toxin decomposes after a few days of exposure to air.Toxic Activity
The active
toxin Resiniferatoxin binds to pain receptors in the same way ascapsaicin but much more powerfully. It stimulates the neurons to fire repeatedly until the neuron dies, causing searing pain and sending the victim into severeanaphylactic shock .Due to its selective nature of binding and killing pain receptors while leaving other
nerve cells intact, resiniferatoxin is currently being researched as a possible treatment forchronic pain .References
ources
[http://www.rirdc.gov.au/reports/EOI/02-001.pdf Growing Milkweed, a plant with prospective anticancer properties] (see pg. 1)
[http://www.mpbio.com/ecom/docs/proddata.nsf/(webtds)/156505 information on Resiniferatoxin]
Nicolaou, K. C. and Snyder, Scott A. Classics in Total Synthesis Vol. II. Wiley VCH, 2003. Chapter 6.
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