- ELMO3
protein
Name = engulfment and cell motility 3
caption =
width =
HGNCid = 17289
Symbol = ELMO3
AltSymbols = CED12, FLJ13824
EntrezGene = 79767
OMIM = 606422
RefSeq = NM_024712
UniProt = Q96BJ8
PDB =
ECnumber =
Chromosome = 16
Arm = q
Band = 22.1
LocusSupplementaryData =Engulfment and cell motility 3, also known as ELMO3, is a human
gene .cite web | title = Entrez Gene: ELMO3 engulfment and cell motility 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79767 | accessdate = ] cite journal | author = Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS | title = CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration | journal = Cell | volume = 107 | issue = 1 | pages = 27–41 | year = 2001 | month = October | pmid = 11595183 | doi = 10.1016/S0092-8674(01)00520-7 | url = | issn = ]The
protein encoded by this gene is similar to a "C. elegans" protein that functions inphagocytosis of apoptotic cells and incell migration . Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 (DOCK1) protein to promote phagocytosis and effect cell shape changes.References
External links
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