VWA2

protein
Name = von Willebrand factor A domain containing 2
caption =


width =
HGNCid = 24709
Symbol = VWA2
AltSymbols = FLJ45857, FLJ16213, CCSP-2, AMACO
EntrezGene = 340706
OMIM =
RefSeq = NM_198496
UniProt = Q5GFL6
PDB =
ECnumber =
Chromosome = 10
Arm = q
Band = 25.3
LocusSupplementaryData =

von Willebrand factor A domain containing 2, also known as VWA2 is a human gene.cite web | title = Entrez Gene: von Willebrand factor A domain containing 2 | url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=340706| accessdate = ] cite journal | author = Sengle G, Kobbe B, Morgelin M, Paulsson M, Wagener R | title = Identification and characterization of AMACO, a new member of the von Willebrand factor A-like domain protein superfamily with a regulated expression in the kidney | journal = J. Biol. Chem. | volume = 278 | issue = 50 | pages = 50240–9 | year = 2003 | month = December | pmid = 14506275 | doi = 10.1074/jbc.M307794200 | url = | issn = ] The protein encoded by this gene is a member of the Von Willebrand factor family of blood coagulation proteins.

Since the expression of the VWA2 protein is markedly induced in colon cancers and since VWA2 is a serum protein, it may be useful as a diagnostic serum marker of early stage colon cancer.cite journal | author = Xin B, Platzer P, Fink SP, Reese L, Nosrati A, Willson JK, Wilson K, Markowitz S | title = Colon cancer secreted protein-2 (CCSP-2), a novel candidate serological marker of colon neoplasia | journal = Oncogene | volume = 24 | issue = 4 | pages = 724–31 | year = 2005 | month = January | pmid = 15580307 | doi = 10.1038/sj.onc.1208134 | url = | issn = ]

References

External links

*