- Beutler test
The Beutler test, also known as the fluorescent spot test, [cite journal |author=Markić J, Krzelj V, Markotić A, "et al" |title=High incidence of glucose-6-phosphate dehydrogenase deficiency in Croatian island isolate: example from Vis island, Croatia |journal=Croat. Med. J. |volume=47 |issue=4 |pages=556–70 |year=2006 |month=August |pmid=16909453 |doi= |url=http://www.cmj.hr/2006/47/4/16909453.htm] is a screening test used to identify enzyme defects. [Beutler E, Baluda MC. A simple spot screening test for galactosemia. J Lab Clin Med 1966;68:137-141.] [Beutler E, Baluda M, Donnell GE. A new method for the detection of galactosemia and its carrier state. J Lab Clin Med 1964;64:695-705.] [Beutler E, Mitchell M. New rapid for the estimation of red cell galactose-1-phosphate uridyl transferase activity. J Lab Clin Med 1968;72:527-532.]
It can be used in screening for:
*galactosemia cite journal |author=Fujimoto A, Okano Y, Miyagi T, Isshiki G, Oura T |title=Mass screening of galactosemia: improved Beutler Test using automated quantitative fluorescence assay |journal=Southeast Asian J. Trop. Med. Public Health |volume=30 Suppl 2 |issue= |pages=69 |year=1999 |pmid=11400789 |doi= |url=] cite journal |author=Fujimoto A, Okano Y, Miyagi T, Isshiki G, Oura T |title=Quantitative Beutler test for newborn mass screening of galactosemia using a fluorometric microplate reader |journal=Clin. Chem. |volume=46 |issue=6 Pt 1 |pages=806–10 |year=2000 |month=June |pmid=10839768 |doi= |url=http://www.clinchem.org/cgi/pmidlookup?view=long&pmid=10839768]*
glucose-6-phosphate dehydrogenase deficiency cite journal |author=Kirimlidis S, Politis E, Drossos C, Scaloumbakas N, Papaioannou M |title=Glucose-6-phosphate-dehydrogenase deficiency in Greece. Study by using a modification of Beutler and Fair- banks spot test |journal=Helv Paediatr Acta |volume=20 |issue=5 |pages=490–6 |year=1965 |month=November |pmid=5895109 |doi= |url=] cite journal |author=DERITIS L |title= [THE FAIRBANKS AND BEUTLER TEST FOR THE ROUTINE DETECTION OF ERYTHROCYTE DEFICIENCY OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE.] |language=Italian |journal=Riv Clin Pediatr |volume=71 |issue= |pages=242–4 |year=1963 |month=April |pmid=14074804 |doi= |url=]References
Further reading
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