Iodomethylzinc iodide

Iodomethylzinc iodide

Iodomethylzinc iodide is the active reagent in the Simmons-Smith reaction. For example, iodomethylzinc iodide, formed "in situ" from diiodomethane and a zinc-copper couple reacts with cyclohexene to give norcarane (bicyclo [4.1.0] heptane).OrgSynth | author = Smith, R. D.; Simmons, H. E. | title = Norcarane | collvol = 5 | collvolpages = 855 | prep = cv5p0855]

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Iodomethylzinc iodide may also be generated by the reaction of diazomethane with zinc iodide, or by the reaction of methylene iodide with diethylzinc.

References


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