3-(p-Fluorobenzoyl)tropane

Drugbox
IUPAC_name = (1R,5S)-(8-methyl-8-azabicyclo [3.2.1] octan-3-yl)-4-fluorobenzoate


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PubChem= 5147770
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C=15 | H=18 | F=1 | N=1 | O=2
molecular_weight = 263.307
smiles = CN1C(C3)CCC1CC3OC(=O)c(cc2)ccc2F
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3-(p-Fluorobenzoyl)tropane, (4-fluorotropacocaine, 3-pseudotropyl-4-fluorobenzoate) is a tropane derivative drug which acts as a stimulant and local anaesthetic, having around 30% the stimulant potency of cocaine but around the same potency as a local anaesthetic.fact|date=August 2008 It has been investigated as a potential radiolabelled agent for studying receptor binding, [Ali M. Emran. New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control. Springer, 1991. p84. ISBN 0306440350] and as a potential neuroleptic drug, [Fontenla JA, Cadavid MI, Orallo F, Eirin A, Calleja JM. Synthesis and study of the possible neuroleptic activity of 3-(p-fluorobenzoyl)-tropane. "Archivos de Farmacologia y Toxicologia". (Spanish) 1984 Dec;10(3):151-60. PMID 6152386] but was not adopted for either of these applications.

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