Large cell lymphoma

Large cell lymphoma

One classification system for lymphomas divides the diseases according to the size of the white blood cells that has turned cancerous. The large cell lymphomas have large cells. A large cell, in this context, has a diameter of 17 to 20 µm.cite book
author=Turgeon, Mary Louise
title=Clinical hematology: theory and procedures
publisher=Lippincott Williams & Wilkins
location=Hagerstown, MD
year=2005
pages=221
isbn=0-7817-5007-5] Other groups of lymphomas in this system are the small cell lymphomas and mixed cell lymphomas.

Diffuse large B cell lymphoma is the most common of the large cell lymphomas. Many other B cell lymphomas feature large cells:

* Angiocentric lymphoma
* Burkitt’s lymphoma
* Follicular large cell lymphoma
* Immunoblastic lymphoma
* Intravascular large cell lymphoma
* Primary mediastinal B cell lymphoma
* T-cell–rich B-cell lymphoma
* Primary splenic lymphoma (rare)
* Primary central nervous system lymphomas, which are often diffuse large B cell lymphomas

Less commonly, a large cell lymphoma may feature T cells. Anaplastic large cell lymphoma is an example of a large cell lymphoma that involves T cells. Of the large-cell T-cell lymphomas, it has the best prognosis.

References


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