GAI (Arabidopsis thaliana gene)

IPC_Protein_box


image_source =
PDB =
Name = GA Insensitive
HGNCid =
Symbol = GAI
AltSymbols = ; AT1G14920 ; F10B6.34; F10B6_34; GA INSENSITIVE; GAI PROTEIN; RESTORATION ON GROWTH ON AMMONIA; RGA2
OMIM =
ECnumber =
Homologene =
MGIid =
GeneModel_

---

GeneAtlas_

Function = GNF_GO|id=GO:0003700 |text = transcription factor activity
Component = GNF_GO|id=GO:0005634 |text = nucleus
Process =GNF_GO|id=GO:0042538 |text = hyperosmotic salinity responseGNF_GO|id=GO:0009938 |text = negative regulation of gibberellic acid mediated signalingGNF_GO|id=GO:0010187 |text = negative regulation of seed germinationGNF_GO|id=GO:0010187 |text = negative regulation of seed germination
Orthologs = IPC_Ortholog_box
Athal_EntrezGene = 838057
Athal_Ensembl =
Athal_RefseqProtein = NP_172945
Athal_RefseqmRNA =  NM_101361
Athal_GenLoc_db = arabidopsis
Athal_GenLoc_chr = Chr1
Athal_GenLoc_start = 5149221
Athal_GenLoc_end = 5151349
Athal_Uniprot = Q9LQT8
Osat_EntrezGene =
Osat_Ensembl =
Osat_RefseqmRNA =
Osat_RefseqProtein =
Osat_GenLoc_db =
Osat_GenLoc_chr =
Osat_GenLoc_start =
Osat_GenLoc_end =
Osat_Uniprot =

GAI, also known as GA INSENSITIVE, is an [http://species.wikimedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] gene.cite web | title = Entrez Gene: GAI| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=838057| accessdate = ]

IPC_Summary
section_title =
summary_text = Similar to a putative transcription factor and transcriptional coactivators. Repressor of GA responses and involved in gibberellic acid mediated signaling. Member of the DELLA proteins that restrain the cell proliferation and expansion that drives plant growth. The protein undergoes degradation in response to GA via 26S proteasome.cite web | title = Entrez Gene: GAI| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=838057| accessdate = ]

References

Further reading

IPC_Further_reading
citations =

*cite journal | author=De Grauwe L, "et al." |title=Reduced gibberellin response affects ethylene biosynthesis and responsiveness in the Arabidopsis gai eto2-1 double mutant. |journal=New Phytol. |volume=178 |issue= 2 |pages= 457 |year= 2008 |pmid= 18078472 |doi=
*cite journal | author=Oh E, "et al." |title=PIL5, a phytochrome-interacting bHLH protein, regulates gibberellin responsiveness by binding directly to the GAI and RGA promoters in Arabidopsis seeds. |journal=Plant Cell. |volume=19 |issue= 4 |pages= 1192-1208 |year= 2007 |pmid= 17449805 |doi=
*cite journal | author=Dill A, "et al." |title=The Arabidopsis F-box protein SLEEPY1 targets gibberellin signaling repressors for gibberellin-induced degradation. |journal=Plant Cell. |volume=16 |issue= 6 |pages= 1392-1405 |year= 2004 |pmid= 15155881 |doi=
*cite journal | author=Fu X, "et al." |title=The Arabidopsis mutant sleepy1gar2-1 protein promotes plant growth by increasing the affinity of the SCFSLY1 E3 ubiquitin ligase for DELLA protein substrates. |journal=Plant Cell. |volume=16 |issue= 6 |pages= 1406-1418 |year= 2004 |pmid= 15161962 |doi=
*cite journal | author=Busov V, "et al." |title=Transgenic modification of gai or rgl1 causes dwarfing and alters gibberellins, root growth, and metabolite profiles in Populus. |journal=Planta. |volume=224 |issue= 2 |pages= 288-299 |year= 2006 |pmid= 16404575 |doi=
*cite journal | author=Cao D, "et al." |title=Loss of function of four DELLA genes leads to light- and gibberellin-independent seed germination in Arabidopsis. |journal=Planta. |volume=223 |issue= 1 |pages= 105-113 |year= 2005 |pmid= 16034591 |doi=

----