Pain wind-up

Pain wind-up

Pain wind-up is a phenomenon where repeated painful stimulation of peripheral nerves at sufficient intensity to stimulate group C nerve fibers leads to progressively increasing electrical response in the corresponding spinal posterior horn neurons. This slow, cumulative effect is partly due to the slow response of NMDA receptors, but may also be linked to sustained release of substance P, a neuropeptide, in the posterior horns.

ee also

*Group C nerve fiber#Central Sensitization
*fibromyalgia

External links

*http://www.myalgia.com/chrpain.htm
*http://courses.washington.edu/conj/sensory/pain.htm


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • Wind power in the European Union — The market for European wind power capacity grew in 2006, according to statistics from the European Wind Energy Association. 7,588 MW of wind power capacity, worth some €9 billion, was installed in the European Union (EU) in 2006, an increase of… …   Wikipedia

  • Wind on Fire — is a fantasy trilogy written by William Nicholson. It is set in a realm similar to ours, but distinctly unrelated to it.PlotThe books are set in a realm similar to ours, but separate. They tell the story of the Hath family, and the Manth people… …   Wikipedia

  • Pain Is So Close to Pleasure — «Pain Is So Close to Pleasure» …   Википедия

  • Wind colic — Colic Col ic, n. [F. colique, fr. L. colicus sick with the colic, Gr. ?, fr. ?, ?, the colon. The disease is so named from its being seated in or near the colon. See {Colon}.] (Med.) A severe paroxysmal pain in the abdomen, due to spasm,… …   The Collaborative International Dictionary of English

  • Chronic prostatitis/chronic pelvic pain syndrome — Chronic nonbacterial prostatitis Classification and external resources ICD 10 N41.1 …   Wikipedia

  • Complex regional pain syndrome — Complex regional pain syndrome/Reflex Sympathetic Dystrophy (CRPS/RSD) Classification and external resources ICD 10 M89.0, G56.4 ICD 9 …   Wikipedia

  • Ode to the West Wind — 1820 publication in the Prometheus Unbound with Other Poems collection. 1820 cover of Pro …   Wikipedia

  • At the Back of the North Wind — infobox Book | name = At the Back of the North Wind title orig = translator = image caption = author = George McDonald illustrator = cover artist = country = United Kingdom language = English series = genre = Children s novels publisher = release …   Wikipedia

  • Chronic pain — ICD 10 R52.1 R52.2 ICD 9 338.2 Chronic pain has several different meanings in medicine. Traditionally, the distinction betwe …   Wikipedia

  • Drawn By Pain — Creator Jesse Cowell Starring Marissa Parness Elizabeth Plevy Guy Rader Michael Speer Jack Perry Sharon Hawk Country …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”