CCT6A

Chaperonin containing TCP1, subunit 6A (zeta 1), also known as CCT6A, is a human gene.cite web | title = Entrez Gene: CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=908| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.cite web | title = Entrez Gene: CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=908| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Segel GB, Boal TR, Cardillo TS, "et al." |title=Isolation of a gene encoding a chaperonin-like protein by complementation of yeast amino acid transport mutants with human cDNA. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=89 |issue= 13 |pages= 6060–4 |year= 1992 |pmid= 1352881 |doi=
*cite journal | author=Dawson SJ, White LA |title=Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin. |journal=J. Infect. |volume=24 |issue= 3 |pages= 317–20 |year= 1992 |pmid= 1602151 |doi=
*cite journal | author=Kubota H, Hynes G, Carne A, "et al." |title=Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin. |journal=Curr. Biol. |volume=4 |issue= 2 |pages= 89–99 |year= 1994 |pmid= 7953530 |doi=
*cite journal | author=Li WZ, Lin P, Frydman J, "et al." |title=Tcp20, a subunit of the eukaryotic TRiC chaperonin from humans and yeast. |journal=J. Biol. Chem. |volume=269 |issue= 28 |pages= 18616–22 |year= 1994 |pmid= 8034610 |doi=
*cite journal | author=Schwartz GJ, Kittelberger AM, Segel GB |title=Cloning of rabbit Cct6 and the distribution of the Cct complex in mammalian tissues. |journal=Exp. Nephrol. |volume=8 |issue= 3 |pages= 152–60 |year= 2000 |pmid= 10810232 |doi=
*cite journal | author=Yokota S, Yanagi H, Yura T, Kubota H |title=Cytosolic chaperonin-containing t-complex polypeptide 1 changes the content of a particular subunit species concomitant with substrate binding and folding activities during the cell cycle. |journal=Eur. J. Biochem. |volume=268 |issue= 17 |pages= 4664–73 |year= 2001 |pmid= 11532003 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gevaert K, Goethals M, Martens L, "et al." |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810
*cite journal | author=Hillier LW, Fulton RS, Fulton LA, "et al." |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782
*cite journal | author=Imai Y, Soda M, Murakami T, "et al." |title=A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death. |journal=J. Biol. Chem. |volume=278 |issue= 51 |pages= 51901–10 |year= 2004 |pmid= 14532270 |doi= 10.1074/jbc.M309655200
*cite journal | author=Bouwmeester T, Bauch A, Ruffner H, "et al." |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97–105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Higo M, Uzawa K, Kouzu Y, "et al." |title=Identification of candidate radioresistant genes in human squamous cell carcinoma cells through gene expression analysis using DNA microarrays. |journal=Oncol. Rep. |volume=14 |issue= 5 |pages= 1293–8 |year= 2005 |pmid= 16211299 |doi=
*cite journal | author=Guo D, Han J, Adam BL, "et al." |title=Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress. |journal=Biochem. Biophys. Res. Commun. |volume=337 |issue= 4 |pages= 1308–18 |year= 2005 |pmid= 16236267 |doi= 10.1016/j.bbrc.2005.09.191

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